Evaluating Disitamab vedotin for breast cancer treatment
Official title: Disitamab Vedotin (RC48-ADC) in Patients With Breast Cancer: a Real-world Study
Run by RenJi Hospital · NCT05851677 · Data updated 2026-11-12
This study is testing how well Disitamab vedotin works and how safe it is for people with breast cancer who have used or are using this treatment.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | RenJi Hospital Academic / other |
| Drugs / interventions | Disitamab |
| Locations | 1 site (Shanghai) |
| Status | Recruiting |
| Started | June 1, 2023 |
| Main results expected | March 2027 |
| Study ends | August 2027 |
| Registry record updated | September 17, 2025 |
| Trial ID | NCT05851677 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients with histologically confirmed breast cancer who have prior or current experience with Disitamab vedotin.
✕Probably not a fit
Patients currently participating in other clinical trials involving Disitamab vedotin may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to assess the efficacy and safety of Disitamab vedotin (RC48-ADC) in patients diagnosed with breast cancer. Participants will include individuals who have either previously used or are currently using this treatment. The study will gather data on patient outcomes and side effects to better understand the drug's impact on breast cancer management.
Why it matters
Potential benefit: If successful, this study could provide valuable insights into the effectiveness of Disitamab vedotin for breast cancer patients.
How similar studies have gone: While this study focuses on a specific treatment, similar approaches have shown promise in other cancer therapies, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Histologically confirmed breast cancer; * Prior or current use of Disitamab vedotin (RC48-ADC); Exclusion Criteria: * Participating in clinical trials involving Disitamab vedotin (RC48-ADC) or not.
Where it's running
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Renji Hospital, School of Medicine, Shanghai Jiaotong University
Shanghai, China Recruiting
Study contacts
- Principal investigator: Wenjin Yin, M.D. — Renji Hospital,School of Medicine, Shanghai Jiaotong University
- Study coordinator: Wenjin Yin, M.D.
- Email: yinwenjin@renji.com
- Phone: 86(21)68385569
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Combining Disitamab Vedotin with RC148 for treating HR-negative, HER2-low breast cancer
This study is testing if a new combination of two treatments can help people with hard-to-treat HR-negative, HER2-low breast cancer feel better compared to standard options.
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Evaluating a new treatment for HR-positive, HER2-low breast cancer
This study is testing a new treatment combining Disitamab Vedotin and Toripalimab with chemotherapy to see if it helps people with HR-positive, HER2-low breast cancer before surgery.
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Neoadjuvant treatment for HR-negative, HER2 low-expressing breast cancer
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Combination therapy for HER2-positive breast cancer
This study tests a new combination of treatments for people with HER2-positive breast cancer to see if it helps them respond better before surgery.
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Gyrotonic exercise for elders with breast cancer and Behcet disease
We’re testing whether a gyrotonic exercise program helps older people who have both Behcet disease and breast cancer.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.