Evaluating Direct Pulp Capping Treatments in Permanent Molars
Comparative Evaluation of the Clinical Outcome of Direct Pulp Capping Treatment Using Bioactive Materials With Diode Laser in Permanent Molars: a Randomized Clinical Trial
This study is testing different treatments for saving the nerves in permanent molars to see which one works best for young adults with deep cavities.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 19 Years to 40 Years |
| Sex | All |
| Sponsor | Kafrelsheikh University Academic / other |
| Locations | 1 site (Kafr ash Shaykh, Kafr El-Shaikh) |
| Trial ID | NCT06599814 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to compare the clinical outcomes of different direct pulp capping treatments in permanent molars. Conducted at Kafrelsheikh University, the study will involve 60 patients aged 19 to 40 who have undergone conservative treatment for deep caries. Participants will be randomly assigned to one of four treatment groups, utilizing either RetroMTA or TheraCal with or without laser assistance. The study will follow ethical guidelines and include thorough patient consent and assessment procedures.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 19 to 40 with vital teeth that have been exposed due to caries removal.
Not a fit: Patients with extensive caries or those with non-vital teeth will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment outcomes for patients requiring vital pulp therapy.
How similar studies have performed: While similar approaches have been explored, this specific comparison of techniques is novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * In all patients, the pulp had been exposed because of caries removal. Data collection included clinical pulp capping respecting the following criteria. Exclusion Criteria: 1. Individuals who are 19 to 40 years old. 2. Permanent teeth that have not been repaired and have extensive caries on their occlusal and proximal surfaces, extending more than two-thirds of the dentin near the pulp. 3. Vital teeth; asymptomatic teeth (not sensitive to pressure, percussion, or palpation, and no spontaneous pain); sinus tract devoid of swelling and abscess; abnormal mobility absent; no history of spontaneous pain; mild, dull, and tolerable pain associated with eating and drinking cold drinks. 4. Ethyl chloride cold tests, gutta-percha heat testing, palpation, percussion, and the lack of radiological symptoms in periapical radiographs are used to assess the life of the teeth prior to treatment. After the stimulus is removed, pain from a pulp test that is triggered by either heat or cold should subside. 5. In periapical radiography, none of the following conditions should be present: normal lamina dura and periodontal ligaments, no internal or external root resorption, and no radiolucency in the furcation area or periapical region. 6. The exposed area's diameter ranges from 0.5 to 1 mm. 7. Participants' acceptance of the research program.
Where this trial is running
Kafr ash Shaykh, Kafr El-Shaikh
- kafrelsheikh University — Kafr ash Shaykh, Kafr El-Shaikh, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.