Evaluating different antibiotic regimens for treating empyema
Evaluation of Efficacy and Safety Parameters of Different Antibiotics Regimens for Management of Empyema
This study is testing different combinations of antibiotics to see which ones work best and are safest for people with empyema.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Sex | All |
| Sponsor | Fayoum University Academic / other |
| Locations | 1 site (Al Fayyum, Faiyum Governorate) |
| Trial ID | NCT06787885 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the efficacy and safety of various antibiotic regimens, including combinations of levofloxacin, clindamycin, cefepime, moxifloxacin, and meropenem, in the treatment of empyema. Patients diagnosed with empyema will receive one of the specified antibiotic treatments, and their clinical outcomes will be monitored to evaluate the effectiveness and safety of these regimens. The study will focus on both the pharmacodynamics and clinical outcomes associated with these treatments.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with a confirmed diagnosis of empyema.
Not a fit: Patients with a known hypersensitivity or allergy to the antibiotics being tested, as well as those who are pregnant or lactating, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective antibiotic treatments for patients suffering from empyema.
How similar studies have performed: While the specific combinations being tested may be novel, similar studies evaluating antibiotic regimens for empyema have shown varying degrees of success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Confirmed Diagnosis of Empyema: Patients with a clinical and radiological diagnosis of Exclusion Criteria: 1 - Hypersensitivity or Allergy to the selected antibiotic: Patients with a known history of hypersensitivity or allergic reactions to used antibiotics. 2- Pregnancy and Lactation
Where this trial is running
Al Fayyum, Faiyum Governorate
- Fayoum University hospital — Al Fayyum, Faiyum Governorate, Egypt (Recruiting)
Study contacts
- Principal investigator: Abdelrahman Ahmed Mohamed, Teaching assistant — Faculty of pharmacy Fayoum University
- Study coordinator: Abdelrahman Ahmed Mohamed, Teaching Assistant
- Email: aa4496@fayoum.edu.eg
- Phone: +0201145154500
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.