Evaluating cryotherapy for fatigue in multiple sclerosis patients

Effectiveness of Partial-body Cryotherapy on the Fatigue of Patients With Multiple Sclerosis During Readaptation Stay

Not applicable Interventional Fondation Ildys · NCT05219201

This study is testing if partial-body cryotherapy can help reduce fatigue in people with multiple sclerosis during their rehab.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorFondation Ildys Academic / other
Locations1 site (Roscoff)
Trial IDNCT05219201 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness of partial-body cryotherapy (PBC) in alleviating fatigue symptoms in patients with multiple sclerosis (MS) during their rehabilitation stay. MS is a chronic condition that often leads to debilitating fatigue, affecting the quality of life for many patients. The study will involve administering PBC sessions to participants who meet specific eligibility criteria, including being in remission from MS. The goal is to determine if PBC can improve fatigue and overall well-being without the adverse effects associated with heat stress.

Who should consider this trial

Good fit: Ideal candidates for this study are men and women aged 18 to 65 with multiple sclerosis in remission and a low disability score.

Not a fit: Patients who are pregnant, have contraindications for cryotherapy, or are unable to complete the program may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce fatigue and improve the quality of life for patients with multiple sclerosis.

How similar studies have performed: While there is limited research on the effectiveness of cryotherapy for MS, similar approaches have shown promise in managing fatigue in other conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* men and woen over 18 years old and under 65 years old
* with multiple sclerosis
* 0-6 points in the expanded disability states scale (EDSS)
* with MS in remission (at least 6 months since the last relapse)
* able to understand and respect the protocol and its requirement
* who signed the consent prior to any other procedure protocol

Exclusion Criteria:

* major patients under guardianship/curators/legal protection
* pregnant patients
* patients with contraindication for cryotherapy
* patients unable to complete the entire program
* patients with substantial change in pharmacological treatment the month before the start of the study

Where this trial is running

Roscoff

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Multiple Sclerosiscryotherapyfatiguequality of lifespasticityquality of sleepdepression symptoms
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.