Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating contrast ultrasound for detecting abdominal trauma complications

Official title: Detection of Post-traumatic Abdominal Pseudoaneurysms by CEUS and CT: A Prospective Comparative Global Study

Run by Niguarda Hospital · NCT05627908 · Data updated 2026-11-12

This study is testing if a special type of ultrasound can better find complications from abdominal injuries in adults compared to the usual CT scans.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment385 (estimated)
SponsorNiguarda Hospital
Academic / other
Locations1 site (Milan, Italia)
StatusRecruiting
StartedOctober 1, 2022
Main results expectedOctober 31, 2026
Study endsDecember 31, 2027
Registry record updatedApril 16, 2026
Trial IDNCT05627908 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older with confirmed blunt or penetrating trauma to the spleen, liver, or kidneys.

Probably not a fit

Patients under 18 years old or those without confirmed abdominal trauma will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the effectiveness of contrast-enhanced ultrasound (CEUS) in identifying post-traumatic pseudoaneurysms in patients with abdominal injuries. Adult patients with confirmed splenic, hepatic, or renal trauma will undergo follow-up assessments using both CEUS and the standard CT scan to compare their efficacy. The study aims to determine if CEUS can serve as a viable alternative to CT scans for monitoring solid organ injuries after trauma. Follow-up evaluations will occur within two to five days post-injury, with additional assessments allowed during the same hospitalization.

Why it matters

Potential benefit: If successful, this study could provide a less invasive and safer method for monitoring abdominal trauma recovery.

How similar studies have gone: While the use of CEUS in trauma assessment is promising, this specific approach comparing it directly to CT scans for follow-up in abdominal trauma is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients (18 years old and above) with proven blunt or penetrating splenic and/or liver and/or renal trauma as shown by a CT scan and classified according to the American Injury Scale American Association for Surgery (AAST) Organ Injury Scale (OIS) will be included

Exclusion Criteria:

* minor to 18 years old

Where it's running

  • ASST GOM Niguarda
    Milan, Italia, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.