Evaluating contrast ultrasound for detecting abdominal trauma complications
Detection of Post-traumatic Abdominal Pseudoaneurysms by CEUS and CT: A Prospective Comparative Global Study
This study is testing if a special type of ultrasound can better find complications from abdominal injuries in adults compared to the usual CT scans.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 385 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Niguarda Hospital Academic / other |
| Locations | 1 site (Milan, Italia) |
| Trial ID | NCT05627908 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the effectiveness of contrast-enhanced ultrasound (CEUS) in identifying post-traumatic pseudoaneurysms in patients with abdominal injuries. Adult patients with confirmed splenic, hepatic, or renal trauma will undergo follow-up assessments using both CEUS and the standard CT scan to compare their efficacy. The study aims to determine if CEUS can serve as a viable alternative to CT scans for monitoring solid organ injuries after trauma. Follow-up evaluations will occur within two to five days post-injury, with additional assessments allowed during the same hospitalization.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with confirmed blunt or penetrating trauma to the spleen, liver, or kidneys.
Not a fit: Patients under 18 years old or those without confirmed abdominal trauma will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive and safer method for monitoring abdominal trauma recovery.
How similar studies have performed: While the use of CEUS in trauma assessment is promising, this specific approach comparing it directly to CT scans for follow-up in abdominal trauma is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult patients (18 years old and above) with proven blunt or penetrating splenic and/or liver and/or renal trauma as shown by a CT scan and classified according to the American Injury Scale American Association for Surgery (AAST) Organ Injury Scale (OIS) will be included Exclusion Criteria: * minor to 18 years old
Where this trial is running
Milan, Italia
- ASST GOM Niguarda — Milan, Italia, Italy (Recruiting)
Study contacts
- Study coordinator: Francesco Virdis, MD
- Email: francesco.virdis@ospedaleniguarda.it
- Phone: +393519639712
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.