Evaluating contrast ultrasound for detecting abdominal trauma complications
Official title: Detection of Post-traumatic Abdominal Pseudoaneurysms by CEUS and CT: A Prospective Comparative Global Study
Run by Niguarda Hospital · NCT05627908 · Data updated 2026-11-12
This study is testing if a special type of ultrasound can better find complications from abdominal injuries in adults compared to the usual CT scans.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 385 (estimated) |
| Sponsor | Niguarda Hospital Academic / other |
| Locations | 1 site (Milan, Italia) |
| Status | Recruiting |
| Started | October 1, 2022 |
| Main results expected | October 31, 2026 |
| Study ends | December 31, 2027 |
| Registry record updated | April 16, 2026 |
| Trial ID | NCT05627908 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older with confirmed blunt or penetrating trauma to the spleen, liver, or kidneys.
✕Probably not a fit
Patients under 18 years old or those without confirmed abdominal trauma will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the effectiveness of contrast-enhanced ultrasound (CEUS) in identifying post-traumatic pseudoaneurysms in patients with abdominal injuries. Adult patients with confirmed splenic, hepatic, or renal trauma will undergo follow-up assessments using both CEUS and the standard CT scan to compare their efficacy. The study aims to determine if CEUS can serve as a viable alternative to CT scans for monitoring solid organ injuries after trauma. Follow-up evaluations will occur within two to five days post-injury, with additional assessments allowed during the same hospitalization.
Why it matters
Potential benefit: If successful, this study could provide a less invasive and safer method for monitoring abdominal trauma recovery.
How similar studies have gone: While the use of CEUS in trauma assessment is promising, this specific approach comparing it directly to CT scans for follow-up in abdominal trauma is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * adult patients (18 years old and above) with proven blunt or penetrating splenic and/or liver and/or renal trauma as shown by a CT scan and classified according to the American Injury Scale American Association for Surgery (AAST) Organ Injury Scale (OIS) will be included Exclusion Criteria: * minor to 18 years old
Where it's running
-
ASST GOM Niguarda
Milan, Italia, Italy Recruiting
Study contacts
- Study coordinator: Francesco Virdis, MD
- Email: francesco.virdis@ospedaleniguarda.it
- Phone: +393519639712
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.