Evaluating complication rates after nipple sparing mastectomy

A Retrospective, Multicenter Study of Open Nipple Sparing Mastectomy (NSM)

Observational Intuitive Surgical · NCT04447339

This study looks at the complication rates after nipple-sparing mastectomy to see how safe and effective the surgery is for patients.

Quick facts

Study typeObservational
Enrollment75 (estimated)
Ages18 Years and up
SexFemale
SponsorIntuitive Surgical Industry-sponsored
Locations5 sites (Evanston, Illinois and 4 other locations)
Trial IDNCT04447339 on ClinicalTrials.gov

What this trial studies

This observational study involves a retrospective, multicenter chart review aimed at assessing the complication rates associated with prophylactic open nipple sparing mastectomy (NSM) procedures. The evaluation will focus on patient outcomes through 42 days postoperatively, utilizing data from multiple healthcare institutions. By analyzing patient records, the study seeks to provide insights into the safety and effectiveness of this surgical approach.

Who should consider this trial

Good fit: Ideal candidates for this study are female patients who have undergone open prophylactic nipple sparing mastectomy between January 1, 2018, and 42 days prior to IRB approval.

Not a fit: Patients who have not undergone nipple sparing mastectomy or those who had surgeries outside the specified timeframe may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of the safety profile of nipple sparing mastectomy, potentially leading to improved surgical practices.

How similar studies have performed: While this study is observational and retrospective, similar studies evaluating surgical outcomes have shown promise in improving patient care and safety.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

All female patients that have undergone open prophylactic NSM cases performed between January 1, 2018 through 42 days prior to IRB approval

Exclusion Criteria:

-

Where this trial is running

Evanston, Illinois and 4 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Nipple Sparing Mastectomy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.