Evaluating cognitive, motor, and sleep issues in stroke patients after thrombectomy

"Cognitive, Motor and Sleep Evaluation in Patients With Ischemic Stroke of Basal Ganglia After Thrombectomy"

NA · Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05878002

This study is testing how a procedure for stroke treatment affects thinking, movement, and sleep problems in patients after their stroke.

Quick facts

PhaseNA
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS (other)
Locations1 site (Rome)
Trial IDNCT05878002 on ClinicalTrials.gov

What this trial studies

This interventional study aims to assess the clinical outcomes of patients who have experienced an acute ischemic stroke treated with mechanical thrombectomy, specifically focusing on the basal ganglia. It will evaluate the prevalence and characteristics of cognitive, motor, and sleep dysfunctions that may arise following the stroke. Participants will undergo assessments during the acute phase and continue with long-term follow-ups to monitor changes over time. The study utilizes polysomnography as part of its evaluation methodology.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older who have suffered an acute ischemic stroke due to proximal middle cerebral artery occlusion and have undergone successful mechanical thrombectomy.

Not a fit: Patients with unstable clinical conditions or a history of cognitive decline prior to the stroke may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of cognitive, motor, and sleep disorders in stroke patients, enhancing their recovery and quality of life.

How similar studies have performed: While there is ongoing research in related areas, this specific approach focusing on cognitive, motor, and sleep evaluations post-thrombectomy is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* participant's age ≥ 18 years
* acute ischemic stroke due to occlusion of proximal middle cerebral artery successfully treated with mechanical thrombectomy (mTICI ≥ 2B)
* signature of specific written informed consent

Exclusion Criteria:

* unstable clinical conditions
* personal history of cognitive decline before the acute ischemic stroke

Where this trial is running

Rome

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Post-stroke Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.