Clinical trial Recruiting at 1 site Observational Ages 18 and up

Evaluating cognitive flexibility tests for depression

Official title: Computational Dissociation of the Causes of Cognitive Rigidity in Depression

Run by University of Minnesota · NCT05736471 · Data updated 2026-11-12

This study is testing new ways to measure how flexible people's thinking is in adults with depression to see if these tests can help better understand their condition.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment2500 (estimated)
SponsorUniversity of Minnesota
Academic / other
Locations1 site (Minneapolis, Minnesota)
StatusRecruiting
StartedFebruary 15, 2023
Main results expectedMay 2, 2027
Study endsMay 2, 2027
Registry record updatedMay 19, 2026
Trial IDNCT05736471 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are English-speaking adults aged 18 and older who reside in the U.S. and have access to an internet-connected computer.

Probably not a fit

Patients who do not speak English or lack internet access may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the psychometric properties of tests designed to evaluate cognitive flexibility in individuals with depression. It will analyze factors such as internal consistency, feasibility, and validity of these tests in measuring cognitive and affective constructs. The study will involve a large sample of adults who meet specific criteria and will utilize online platforms for data collection. By understanding cognitive rigidity, the research seeks to enhance the tools available for studying mental disorders.

Why it matters

Potential benefit: If successful, this study could improve the assessment and understanding of cognitive flexibility in patients with depression, leading to better-targeted interventions.

How similar studies have gone: While this approach is focused on psychometric evaluation, similar studies have shown success in validating cognitive assessments in mental health contexts.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults 18 years or older
* English-speaking
* Live in the U.S.
* Have access to an internet connected computer
* Users of the mTurk and Prolific survey website

Exclusion Criteria:

* NA

Where it's running

  • University of Minnesota
    Minneapolis, Minnesota, United States
    Recruiting

Study contacts

  • Principal investigator: Alexander Herman — University of Minnesota
  • Study coordinator: Matthew Maple
  • Email: maple036@umn.edu
  • Phone: 612-946-1424

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.