Evaluating Ciprofol for Anesthesia in Heart Surgery
Official title: Safety and Effectiveness of Ciprofol in Cardiac Surgery Anesthesia
Run by Shanghai East Hospital of Tongji University · NCT05892471 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study tests if a new anesthetic called ciprofol can make heart surgery safer and more comfortable for older patients compared to the usual anesthetic.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 75 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Shanghai East Hospital of Tongji University Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT05892471 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are elective surgery patients aged 55 to 75 with New York Heart Association class II or III cardiac functions.
✕Probably not a fit
Patients with a history of benzodiazepine allergy, significant liver or kidney insufficiency, or other specified exclusions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the safety and effectiveness of ciprofol, a new intravenous anesthetic, in patients undergoing cardiac surgery. Ciprofol is designed to provide rapid onset and reduced injection pain while minimizing cardiovascular effects. The study will compare ciprofol to the standard anesthetic, propofol, in elective surgery patients aged 55 to 75 with specific cardiac function classifications. The goal is to determine if ciprofol can improve anesthesia outcomes in this high-risk population.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective anesthesia options for patients undergoing cardiac surgery.
How similar studies have gone: While ciprofol is a novel approach, similar studies on alternative anesthetics have shown promising results, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Elective surgery patients 2. Aged 55 to 75 3. New York Heart Association class II or III cardiac functions 4. Median sternotomy approach for coronary artery bypass grafting or heart valve replacement procedures. Exclusion Criteria: 1. With a history of benzodiazepine allergy 2. Significant liver or kidney insufficiency 3. Coagulation dysfunction 4. Neurological or psychiatric disorders 5. Undergone major surgery within the past three months.
Where it's running
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Shanghai East Hospital of Tongji University
Shanghai, Shanghai, China Recruiting
Study contacts
- Study coordinator: Le Yu
- Email: 907084943@qq.com
- Phone: 19921875120
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.