Evaluating Ciprofol for Anesthesia in Heart Surgery
Safety and Effectiveness of Ciprofol in Cardiac Surgery Anesthesia
This study tests if a new anesthetic called ciprofol can make heart surgery safer and more comfortable for older patients compared to the usual anesthetic.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 55 Years to 75 Years |
| Sex | All |
| Sponsor | Shanghai East Hospital of Tongji University Academic / other |
| Locations | 1 site (Shanghai, Shanghai) |
| Trial ID | NCT05892471 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the safety and effectiveness of ciprofol, a new intravenous anesthetic, in patients undergoing cardiac surgery. Ciprofol is designed to provide rapid onset and reduced injection pain while minimizing cardiovascular effects. The study will compare ciprofol to the standard anesthetic, propofol, in elective surgery patients aged 55 to 75 with specific cardiac function classifications. The goal is to determine if ciprofol can improve anesthesia outcomes in this high-risk population.
Who should consider this trial
Good fit: Ideal candidates are elective surgery patients aged 55 to 75 with New York Heart Association class II or III cardiac functions.
Not a fit: Patients with a history of benzodiazepine allergy, significant liver or kidney insufficiency, or other specified exclusions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to safer and more effective anesthesia options for patients undergoing cardiac surgery.
How similar studies have performed: While ciprofol is a novel approach, similar studies on alternative anesthetics have shown promising results, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Elective surgery patients 2. Aged 55 to 75 3. New York Heart Association class II or III cardiac functions 4. Median sternotomy approach for coronary artery bypass grafting or heart valve replacement procedures. Exclusion Criteria: 1. With a history of benzodiazepine allergy 2. Significant liver or kidney insufficiency 3. Coagulation dysfunction 4. Neurological or psychiatric disorders 5. Undergone major surgery within the past three months.
Where this trial is running
Shanghai, Shanghai
- Shanghai East Hospital of Tongji University — Shanghai, Shanghai, China (Recruiting)
Study contacts
- Study coordinator: Le Yu
- Email: 907084943@qq.com
- Phone: 19921875120
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.