Evaluating changes in jawbone after tooth extraction with different preservation methods
Dimensional Changes After Different Alveolar Ridge Preservation Techniques for Posterior Region: Randomized Controlled Trial
This study is testing different ways to preserve jawbone after tooth extraction to see which method works best for people getting their premolars or molars removed.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Campinas, Brazil Academic / other |
| Locations | 1 site (Piracicaba, São Paulo) |
| Trial ID | NCT06081296 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to assess the dimensional changes in soft tissue and alveolar ridge following the extraction of premolar and molar teeth using various alveolar preservation techniques. Eighty participants will be randomly assigned to one of four groups: a control group with traditional closure, a group receiving a mixed free gingival graft, a group with a bone graft and mixed free gingival graft, and a group utilizing a bone graft with a titanium seal. Cone Beam Computed Tomography will be employed to measure bone tissue height before and after the procedures, allowing for a detailed comparison of the effectiveness of each method.
Who should consider this trial
Good fit: Ideal candidates include individuals over 18 years old in good systemic health requiring extraction of premolar or molar teeth with sufficient bone support.
Not a fit: Patients with periodontal disease, smokers, pregnant or lactating women, and those undergoing orthodontic treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve post-extraction outcomes and enhance the preservation of alveolar bone, leading to better dental restoration options for patients.
How similar studies have performed: Previous studies have shown promising results with various alveolar preservation techniques, indicating potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Systemic health (Hypertension and Diabetes controlled) * Indication of tooth extraction with at least 2/3 of the bone support, in the premolar or molar region * Signing the consent form * Individuals over 18 years of age. Exclusion Criteria: * Presence of periodontal disease at the time of surgery * Pregnant and lactating women * Smokers * Being in orthodontic treatment * Use medication that alters the bone healing process, such as those used to treat osteoporosis and the bisphosphonate group * Individuals under 18 years of age
Where this trial is running
Piracicaba, São Paulo
- Piracicaba Dental School — Piracicaba, São Paulo, Brazil (Recruiting)
Study contacts
- Principal investigator: Renato Casarin, PhD — University of Campinas, Brazil
- Study coordinator: Renato Casarin, PhD
- Email: casarinrcv@yahoo.com
- Phone: +55 (19) 2106-5220
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.