Evaluating CDK4/6 inhibitors for advanced breast cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the survival outcomes and adverse events associated with CDK4/6 inhibitors in patients diagnosed with hormone receptor-positive advanced breast cancer. It will also investigate potential predictive biomarkers that may influence treatment efficacy. The study is ambispective and conducted at a single center, focusing on patients who have either received or are planning to receive CDK4/6 inhibitors for their advanced disease. Participants will be monitored for their health outcomes and any side effects experienced during treatment.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged ≥18 and older
* Confirmed diagnosis of hormone receptor-positive breast cancer.
* Subjects with locoregionally recurrent or metastatic disease not amenable to curative therapy.
* Subjects have received or plan to receive CDK4/6 inhibitors for advanced disease.
* ECOG 0-2
* Adequate organ function

Exclusion Criteria:

* Subjects disable to swallow pills.
* History of immunodeficiency disease

Where it's running

• Renji Hospital, School of Medicine, Shanghai Jiao Tong University
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Study coordinator: Ziping Wu, MD
• Email: wuziping@renji.com
• Phone: 86(21)68385569

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.