Evaluating bone loss and defects during accelerated orthodontic treatment

Comparison of Alveolar Bone Dehiscence and Fenestration Following Maxillary Canine Retraction Using Two Methods of Tooth Movement Acceleration. A Randomized Clinical Trial

This study is testing two methods to see if they can help adults undergoing fast orthodontic treatment avoid bone problems that could affect their teeth.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 60 (estimated)
• Ages: 16 Years to 22 Years
• Sex: All
• Sponsor: Tanta University (other)
• Locations: 1 site (Tanta)
• Trial ID: NCT06500559 on ClinicalTrials.gov

What this trial studies

This study investigates the occurrence of alveolar bone dehiscence and fenestration in patients undergoing accelerated maxillary canine retraction. It employs two methods—platelet-rich plasma (PRP) injection and decortication—to enhance tooth movement and minimize complications associated with orthodontic therapy. The focus is on understanding how these interventions can reduce bone defects that may lead to root exposure and treatment failure. The study aims to provide insights into effective strategies for improving orthodontic outcomes, particularly in adult patients.

Who should consider this trial

Good fit: Ideal candidates are healthy individuals aged 16 to 22 with specific malocclusions requiring maxillary canine retraction.

Not a fit: Patients with severe crowding, previous orthodontic treatment, or those who are medically compromised may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved orthodontic treatment outcomes by reducing complications associated with bone loss.

How similar studies have performed: While the use of PRP and decortication in orthodontics is promising, further research is needed to establish their effectiveness, making this approach somewhat novel.

Eligibility criteria

Inclusion Criteria:

1. Age of the patients ranged from 16: 22 years old.
2. Malocclusion that requires extraction of the maxillary first premolar and canine retraction (e.g. class I bimaxillary dentoalveolar protrusion and class II div 1 malocclusion).
3. Maximum anchorage needed for the maxillary arch as a part of the orthodontic treatment plan.
4. Good oral hygiene and periodontal condition.

Exclusion Criteria:

1. Medically compromised patients.
2. Severe crowding in the maxillary arch.
3. Chronic intake of NSAIDs or any medication that interfere with OTM.
4. Previous orthodontic treatment.

Where this trial is running

Tanta

• Tanta University — Tanta, Egypt (RECRUITING)

Study contacts

• Study coordinator: Safa B Alawy, PhD

Conditions: Fenestration, Dehiscence, accelerated orthodontics, fenestration, CBCT