Evaluating bone density using ultrasound technology compared to DXA
Official title: REMS Versus DXA for Bone Mineral Density (BMD) Evaluation
Run by Echolight S.p.A. · NCT06371755 · Data updated 2026-11-12
This study is testing a new ultrasound method to see if it can accurately measure bone density in women aged 30-80 compared to the standard DXA scan.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 30 Years to 80 Years |
| Sex | Women only |
| Enrollment | 296 (estimated) |
| Sponsor | Echolight S.p.A. Industry-sponsored |
| Locations | 1 site (Milan, MI) |
| Status | Recruiting |
| Started | November 19, 2019 |
| Main results expected | December 31, 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | September 5, 2025 |
| Trial ID | NCT06371755 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 30-80 who are scheduled for lumbar and/or femoral DXA examinations.
✕Probably not a fit
Patients who are male, have severe walking difficulties, or are outside the age range of 30-80 years will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of Radiofrequency Echographic Multi Spectrometry (REMS) ultrasound technology for assessing bone density in comparison to the standard Dual X-ray Absorptiometry (DXA). It focuses on measuring the intra- and inter-operator repeatability of REMS at the lumbar spine and proximal femur. The study will enroll women aged 30-80 years who are scheduled for DXA examinations and will analyze the diagnostic accuracy of REMS against DXA results. Participants will undergo ultrasound scans, and the results will be compared to DXA reports to classify patients as osteoporotic or non-osteoporotic.
Why it matters
Potential benefit: If successful, this study could provide a non-invasive and more accessible method for diagnosing osteoporosis.
How similar studies have gone: Other studies have shown promising results with ultrasound technologies for bone density evaluation, but this specific approach using REMS is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients scheduled for lumbar and/or femoral DXA examination, * female sex, * age range 30-80 years (for repeatability study), age range 50-70 years (for accuracy study), * absence of severe obesity (BMI \< 40 kg/m2), * absence of severe walking difficulties, * cognitive underwriting of informed consent. Exclusion Criteria: * Male sex, * severe walking difficulties, * age below 30 years or over 80 years, * severe obesity (BMI \> 40 kg/m2), * declared pregnancy.
Where it's running
-
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Milan, Mi, Italy Recruiting
Study contacts
- Principal investigator: Luca M. Sconfienza, Professor — Irccs
- Study coordinator: Carmelo Messina, Professor
- Email: carmelomessina.md@gmail.com
- Phone: 0039 02 8350 1406
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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REMS testing for osteoporosis diagnosis and fracture risk in adults compared with DXA
This study tests whether REMS can diagnose osteoporosis and predict fracture risk in adults who are being evaluated for bone health, using DXA as the standard reference.
-
Automated bone age estimation from routine abdominal CT using AI
This project will try to use routine noncontrast abdominal CT scans and deep learning to estimate bone age in adults who had these scans for other medical reasons.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.