Evaluating body fat changes and sleep apnea resolution after bariatric surgery
Changes in Body Fat and Morphologic Characteristics Associated With Obstructive Sleep Apnea (OSA) Resolution After Bariatric Surgery
This study is testing if losing body fat after bariatric surgery helps people with severe obesity and sleep apnea get better and possibly stop needing their CPAP machines.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 99 Years |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire Saint Pierre Academic / other |
| Locations | 2 sites (Brussels and 1 other locations) |
| Trial ID | NCT05315752 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the relationship between biometric changes and the resolution of obstructive sleep apnea (OSA) in patients undergoing bariatric surgery. Candidates for the study are individuals with severe obesity and diagnosed OSA who are currently using Continuous Positive Air Pressure (CPAP) therapy. The study will follow participants for 2, 6, and 12 months post-surgery to evaluate changes in neck circumference, waist/hip ratio, and body composition, comparing these metrics to changes in body mass index (BMI). The goal is to determine if these biometric changes correlate more strongly with OSA resolution than BMI alone.
Who should consider this trial
Good fit: Ideal candidates are individuals with severe obesity (BMI≥35-40) or morbid obesity (BMI≥40) who have been diagnosed with obstructive sleep apnea and require CPAP treatment.
Not a fit: Patients with cognitive impairments or language barriers that prevent informed consent may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into more effective treatment strategies for OSA in obese patients post-bariatric surgery.
How similar studies have performed: Previous studies have shown significant improvements in OSA resolution following bariatric surgery, indicating that this approach has been successful in similar contexts.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Any informed person who is * eligible for bariatric surgery: with severe obesity (BMI≥35-40) or morbid obesity (BMI≥40), with co-morbidities, who have not lost enough weight with prior lifestyle adaptations (balanced diet, physical activity) AND * with diagnosed obstructive sleep apnoea (OSA) (AHI \> 15/hr on polysomnography) AND * requiring treatment with Continuous Positive Air Pressure (CPAP) Exclusion Criteria: * Cognitive impairment - language barrier
Where this trial is running
Brussels and 1 other locations
- CHU St Pierre — Brussels, Belgium (Recruiting)
- Ionela Bold — Brussels, Belgium (Recruiting)
Study contacts
- Study coordinator: Marie BRUYNEEL, Prof.
- Email: marie.bruyneel@stpierre-bru.be
- Phone: +3225353686
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.