Evaluating blood transfusion effects in trauma patients
Transfusion for Major Haemorrhage in Trauma - Characteristics and Outcomes
This study looks at how early blood transfusions affect trauma patients in Sweden to see if they help with recovery compared to those who don’t get transfusions.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Sex | All |
| Sponsor | Karolinska University Hospital Academic / other |
| Locations | 1 site (Stockholm) |
| Trial ID | NCT05573841 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the characteristics and outcomes of trauma patients receiving early blood transfusions at a Level 1 trauma center in Sweden. It will compare the effects on the coagulation system and overall outcomes between patients who receive transfusions and those who do not. Additionally, the study will evaluate the differences in outcomes for patients receiving prehospital transfusions versus those who start transfusions after hospital admission. The goal is to enhance understanding of optimal care for bleeding patients.
Who should consider this trial
Good fit: Ideal candidates for this study are trauma patients admitted to the trauma unit at Karolinska University Hospital.
Not a fit: Patients with injuries from hanging, drowning, burns, or smoke inhalation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment protocols for trauma patients experiencing major hemorrhage.
How similar studies have performed: While there have been studies on blood transfusion in trauma, this specific approach focusing on early transfusion effects is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All trauma patients admitted to the trauma unit at the Karolinska University Hospital Solna. Exclusion Criteria: * Patients with injuries från hanging, drowning, burns or smoke inhalation.
Where this trial is running
Stockholm
- Karolinska University Hospital — Stockholm, Sweden (Recruiting)
Study contacts
- Study coordinator: Magnus Hedberg, MD/PhD
- Email: magnus.hedberg@regionstockholm.se
- Phone: +46706595989
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.