Evaluating blood pressure response to isometric exercise with blood flow restriction
Blood Pressure Responses to Isometric Blood Flow Restriction Exercise
This study is testing how different types of handgrip exercises with and without blood flow restriction affect blood pressure and heart health in healthy young adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 40 Years |
| Sex | All |
| Sponsor | University of Texas at Austin Academic / other |
| Locations | 1 site (Austin, Texas) |
| Trial ID | NCT06529068 on ClinicalTrials.gov |
What this trial studies
This interventional study aims to assess the acute effects of isometric blood flow restriction (BFR) exercise on blood pressure and cardiovascular functions in healthy young adults. Participants will engage in isometric handgrip exercises under three different conditions: no cuff, BFR with a wide-rigid cuff, and BFR with a narrow-elastic band. The study seeks to determine if BFR exercise leads to greater cardiovascular responses compared to the control condition. The research involves three laboratory visits for participants to perform the exercises.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy young adults aged 18 to 40 who can provide informed consent.
Not a fit: Patients with cardiovascular conditions, diabetes, or other significant health issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into effective exercise strategies for managing blood pressure and improving cardiovascular health.
How similar studies have performed: While the specific approach of using isometric BFR exercise is relatively novel, similar studies have shown promising results in understanding cardiovascular responses to exercise.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: - Apparently healthy young adults aged between 18 - 40 years old and signed the informed consent. Exclusion Criteria: * Abnormal clotting times * Acid-base imbalance/acidosis * Arterial calcification * Atherosclerotic vessels * Cardiopulmonary conditions * Diabetes * Dialysis/central venous access * General/local infection * High intracranial pressure * Hip, pelvis, or femur fracture * History of venous thromboembolism * Hypertension * Immobility for greater than 48 hours in the past month * Immobilizing cast * Implanted medical device * Lymphectomies * Obesity * Open fracture * Open or unhealed soft tissue injuries * Paralysis * Peripheral vascular disease * Pregnancy/postpartum * Prior revascularization * Renal compromise * Severe crush injuries * Sickle cell trait/anemia * Skin grafts * Stroke * Temporary nerve damage * Thrombophilia * Tumor/cancer * Varicose veins * Vascular grafting
Where this trial is running
Austin, Texas
- Cardiovascular Aging Research Laboratory — Austin, Texas, United States (Recruiting)
Study contacts
- Study coordinator: Hirofumi Tanaka, PhD
- Email: htanaka@austin.utexas.edu
- Phone: 5122324801
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.