Evaluating Bleomycin and Cryotherapy for Treating Plantar Warts
Official title: A Randomized Controlled Trial to Evaluate the Effectiveness of Bleomycin and Cryotherapy in Treating Plantar Warts.
Run by The Fourth Affiliated Hospital of Zhejiang University School of Medicine · NCT06718192 · Data updated 2026-11-12
This study is testing whether a bleomycin injection or cryotherapy works better for treating plantar warts in adults aged 18 to 65.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 70 (estimated) |
| Sponsor | The Fourth Affiliated Hospital of Zhejiang University School of Medicine Academic / other |
| Locations | 1 site (Yiwu, Zhejiang) |
| Status | Recruiting |
| Started | December 25, 2024 |
| Main results expected | June 30, 2025 |
| Study ends | June 30, 2025 |
| Registry record updated | March 24, 2025 |
| Trial ID | NCT06718192 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18-65 with diagnosed plantar warts who meet specific inclusion criteria.
✕Probably not a fit
Patients who have had recent local treatment for warts, are immunocompromised, or have certain medical conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to compare the effectiveness of two treatments, bleomycin injection and cryotherapy, for plantar warts. Patients aged 18-65 with diagnosed plantar warts will be randomly assigned to receive either treatment. The study will utilize dermoscopy to assess the efficiency of both therapies and will analyze the data statistically to draw conclusions about their safety, economic burden, and impact on quality of life. The goal is to determine which treatment is more effective for patients suffering from this condition.
Why it matters
Potential benefit: If successful, this study could provide patients with a more effective treatment option for plantar warts.
How similar studies have gone: Other studies have explored treatments for plantar warts, but the specific combination of bleomycin and cryotherapy in this context is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age 18-65 years old, gender is not limited; Consistent with the diagnosis of plantar warts; Volunteer for treatment and sign informed consent; Consent to photograph the lesion; The treatment target area can be selected (the target area must meet the following conditions: The distance between adjacent warts in the target area is \>0.5cm; The diameter of a single wart in the target area is ≤1.5cm, and/or the diameter of a wart mass is ≤1.5cm; The number of total warts/wart masses in the target area is ≤10). Exclusion Criteria: Patients who can't sign informed consent; Had previously received local treatment for common warts within 1 month; hiv-positive patient; Pregnant and lactating women; Has peripheral vascular disease; Allergic to bleomycin; People who are severely immunocompromised, or who are taking immunosuppressive drugs; Mental illness or cognitive incapacity; Other conditions deemed unsuitable for inclusion, such as inability to cooperate with follow-up, were considered by the researchers.
Where it's running
-
The Fourth Affiliated Hospital Zhejiang University School of Medicine
Yiwu, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Lunfei Liu, Master
- Email: liulunfei_zeyy@163.com
- Phone: 17816698735
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.