Evaluating bladder tumor stiffness using ultrasound elastography
Elastographic Analysis of Urothelial Bladder Tumours. Correlation of Elastography With Urodynamic Study and Tumour Grade
This study is testing if a special ultrasound can measure how stiff bladder tumors are to help doctors better understand and plan treatment for patients.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Tours Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Tours) |
| Trial ID | NCT06225726 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the stiffness of urothelial bladder tumors through ultrasound elastography, comparing the results with cystometry parameters and tumor grade. The study utilizes the Aixplorer system to measure ShearWave Elasticity (SWE), which has shown promise in differentiating tumor grades in other types of cancers. By improving the preoperative evaluation of bladder tumors, the study seeks to enhance diagnostic accuracy and treatment planning for patients. Participants will undergo a non-invasive ultrasound procedure to gather data on their bladder tumors.
Who should consider this trial
Good fit: Ideal candidates for this study are adults over 18 years old with bladder tumors visualized on imaging or estimated to be larger than 2 cm.
Not a fit: Patients with a BMI over 30 kg/m2, those who have undergone previous bladder or prostate surgery, or those with prior intravesical treatments may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more accurate preoperative assessments of bladder tumor grades, potentially improving treatment outcomes.
How similar studies have performed: While there has been limited research on elastography for bladder tumors, some studies have shown significant correlations between elastography and tumor grading in other cancers, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \> 18 years * Bladder tumour visualised on abdominal ultrasound or estimated to be more than 2 cm in diameter by fibroscopy or CT scan * Primary resection Exclusion Criteria: * BMI \> 30 kg/m2, * Bladder catheterisation, * Previous bladder or prostate surgery, * Previous intravesical instillation (BCG / Ametycine) * Previous pelvic radiotherapy, * Person having objected to data processing.
Where this trial is running
Tours
- University hospital — Tours, France (Recruiting)
Study contacts
- Principal investigator: Franck BRUYERE — University Hospital
- Study coordinator: Franck BRUYERE
- Email: f.bruyere@chu-tours.fr
- Phone: 247474372
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.