Evaluating bentonite clay gel for bone regeneration in dental defects
Assessing the Clinical Efficacy of Bentonite Clay Gel on Bone Regeneration in the Treatment of Intra-bony Defects: A Clinico-radiograph Study
This study is testing if a new bentonite clay gel mixed with a bone-building material can help people heal better after dental surgery for bone defects compared to just using the bone-building material alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | SVS Institute of Dental Sciences Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Mahbūbnagar, Telangana) |
| Trial ID | NCT06439264 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the effectiveness of bentonite clay gel combined with hydroxyapatite in promoting bone regeneration in patients with intra-bony defects. Participants will undergo flap surgery, where the test group will receive the bentonite gel with hydroxyapatite, while the control group will receive only hydroxyapatite. The study will compare the clinical and radiographic outcomes between the two groups to determine the efficacy of the bentonite gel treatment.
Who should consider this trial
Good fit: Ideal candidates are systemically healthy adults over 18 years with specific types of intra-bony defects and probing pocket depths of 5mm or more.
Not a fit: Patients who are medically compromised, under 18 years old, pregnant, heavy smokers, or have undergone radiotherapy or chemotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could enhance bone regeneration in dental procedures, leading to improved patient outcomes.
How similar studies have performed: While the use of hydroxyapatite is established, the specific combination with bentonite clay gel is novel and has not been extensively tested in similar studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Systemically healthy male and female patients of age \>18 years 2. two-walled or three-walled intrabony defects and 3. probing pocket depths (PPD) of ≥ 5mm. Exclusion Criteria: 1. Medically compromised patients, 2. patients \<18 years of age, 3. pregnant women, 4. heavy smokers, and 5. patients who underwent radiotherapy or chemotherapy are excluded.
Where this trial is running
Mahbūbnagar, Telangana
- Svs Dental College — Mahbūbnagar, Telangana, India (Recruiting)
Study contacts
- Study coordinator: Dr.viswa chandra MDS
- Email: viswachandra@hotmail.com
- Phone: 9912161007
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.