Evaluating Baduanjin for managing elevated blood pressure

Traditional Exercise as Convenient Approach to Improve Health 1-Baduanjin Lower Elevated Blood PreSsure Study

This study is testing if practicing Baduanjin, a traditional Chinese exercise, can help people aged 40 and older with high normal blood pressure improve their overall health and well-being.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 216 (estimated)
• Ages: 40 Years and up
• Sex: All
• Sponsor: China National Center for Cardiovascular Diseases (other gov)
• Locations: 1 site (Beijing, Beijing)
• Trial ID: NCT05397535 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effects of Baduanjin, a traditional Chinese exercise, on individuals with high normal blood pressure. Participants will engage in Baduanjin and brisk walking to evaluate changes in blood pressure, glucose and lipid metabolism, quality of life, psychological well-being, exercise capacity, immune inflammation, endothelial function, and arterial stiffness. The study will include individuals aged 40 and older with specific blood pressure readings, while excluding those with a history of hypertension or certain medical conditions.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 40 years or older with systolic blood pressure between 130-139 mmHg and diastolic blood pressure between 85-89 mmHg.

Not a fit: Patients with a diagnosis of hypertension or significant cardiovascular diseases will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-pharmacological approach to managing elevated blood pressure and improving overall health.

How similar studies have performed: Other studies have shown positive effects of exercise interventions on blood pressure, suggesting potential success for this approach.

Eligibility criteria

Inclusion Criteria:

* Age 40 years or older;
* Systolic blood pressure (SBP) \<140 mmHg and diastolic blood pressure (DBP) \<90 mmHg
* SBP 130-139 mmHg, and/or DBP 85-89 mmHg

Exclusion Criteria:

* Diagnosis of hypertension (SBP≥140 mmHg, and/or DBP ≥90mmHg）
* History of cardiovascular diseases, such as coronary heart disease, heart failure, stroke, and peripheral vascular disease
* Diagnosis of chronic kidney disease, primary aldosteronism, Cushing's syndrome, or pheochromocytoma
* Newly diagnosed cancer or cancer metastasis within 5 years
* History of autoimmune disease
* Having taken antihypertensive drugs or immunoregulators within 2 weeks
* A long-term need for antihypertensive drugs or immunomoregulators
* Unable to maintain moderate intensity exercise due to illness or other reasons
* Pregnant, breastfeeding, or planning to become pregnant within the next 1 year
* Currently taking regular exercise (at least 30 minutes of moderate-intensity exercise at least three times a week)
* Allergic to sports bracelets
* Having participated or been participating in other clinical trials within the last 3 months
* Unable to use smartphones
* Other factors that may affect the follow-up, such as alcohol or substance abuse in the last 12 months, planing to live out of town for a long time, or diagnosis of dementia or cognitive impairment which indicates incapability of completing the study
* Unable to accurately measure blood pressure using the sphygmomanometer provided by the study due to a too large or too small arm circumference

Where this trial is running

Beijing, Beijing

• Fuwai Hospital — Beijing, Beijing, China (RECRUITING)

Study contacts

• Principal investigator: Jing Li, MD,PhD — National Center for Cardiovascular Diseases
• Study coordinator: Jing Li, MD,PhD

Conditions: Elevated Blood Pressure, Baduanjin, elevated blood pressure, antihypertensive effect, randomized controlled trial