Evaluating axillary lymph nodes in breast cancer patients using CT and ultrasound
Evaluation of Axillary Lymph Nodes Using Prone Positioning Computed Tomography Scan and Ultrasound in Patients With Breast Cancer
This study tests if using CT scans and ultrasound can help doctors better understand the condition of lymph nodes in breast cancer patients before surgery to improve treatment and avoid unnecessary procedures.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 500 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | Female |
| Sponsor | Shengjing Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Shenyang, Liaoning) |
| Trial ID | NCT05346510 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the status of axillary lymph nodes in patients with operable breast cancer using prone positioning computed tomography (CT) scans and Doppler ultrasound. By accurately identifying the presence of metastasis in lymph nodes before surgery, the study seeks to improve treatment planning and reduce complications associated with unnecessary lymph node dissections. A total of 500 patients will be recruited, and various comparisons will be made between different lymph node statuses based on imaging results. Statistical methods will be employed to evaluate the significance of findings across groups.
Who should consider this trial
Good fit: Ideal candidates are newly diagnosed patients with operable breast cancer who meet specific imaging and surgical criteria.
Not a fit: Patients with a history of other benign or malignant tumors causing axillary lymphadenopathy may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate staging and treatment plans for breast cancer patients, potentially reducing surgical complications.
How similar studies have performed: While this approach is based on established imaging techniques, the specific use of prone positioning in this context is novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preoperative chest CT and axillary Doppler ultrasound examination in the prone position * Perform ALND * Regular post surgery follow-up (short-term and long-term) Exclusion Criteria: •History of other benign or malignant tumors causing axillary lymphadenopathy
Where this trial is running
Shenyang, Liaoning
- Liaoning Oncology Hospital — Shenyang, Liaoning, China (Recruiting)
Study contacts
- Principal investigator: Jianyi Li, Dr — Cancer Hospital of China Medical University, Liaoning Cancer Hospital
- Study coordinator: Jianyi Li, Dr
- Email: sjbreast@yeah.net
- Phone: 8618940257177
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.