Evaluating antibiotic treatment after joint revision surgery for infection

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter prospective cohort study aims to assess the efficacy of antibiotic treatment following two-stage revision surgery for periprosthetic joint infection (PJI). Eligible patients, diagnosed with PJI and having undergone spacer implantation, will receive a tailored antibiotic regimen based on their clinical evaluation after the second stage of surgery. Participants will be monitored at multiple time points over a two-year period to evaluate infection control rates and treatment outcomes. The study seeks to provide insights into optimal antibiotic courses for managing PJI post-revision surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- 1. A diagnosis of PJI was made according to MSIS criteria. 2. Received spacer implantation and a full course of antibiotic treatment (at least 6 weeks), the patient was clinically determined to have infection control and underwent secondary joint revision.

3\. Age ≥18 years old. 4. The patient voluntarily participated in the study, and was physically and mentally tolerant to the treatment process and various tests of the study. He has signed an informed consent form and passed the examination of all the hospital ethics committees participating in the study.

Exclusion Criteria:

* 1\. Follow-up data not available. 2. Researchers judge that patients no longer meet the standards of the study due to compliance problems

Where it's running

• The First Affiliated Hospital of Fujian Medical University
  Fuzhou, Fujian, China Recruiting

Study contacts

• Study coordinator: Fang
• Email: 9738006@qq.com
• Phone: 18084768503

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.