Evaluating and treating eye diseases
Official title: Studies of the Natural History, Pathogenesis and Outcome of Ocular Disorders
Run by National Institutes of Health Clinical Center (CC) · NCT02821767 · Data updated 2026-11-12
This study is testing standard treatments for different eye diseases in people to see how well they work and to gather information for future research.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 2 Years to 100 Years |
| Sex | All |
| Enrollment | 1000 (estimated) |
| Sponsor | National Institutes of Health Clinical Center (CC) NIH |
| Locations | 1 site (Bethesda, Maryland) |
| Status | Recruiting |
| Started | August 3, 2016 |
| Main results expected | July 1, 2027 |
| Study ends | July 1, 2027 |
| Registry record updated | October 13, 2026 |
| Trial ID | NCT02821767 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include individuals with diagnosed, undiagnosed, or suspected eye diseases who can provide informed consent.
✕Probably not a fit
Patients with systemic diseases that hinder adequate ophthalmologic examination or treatment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The National Eye Institute (NEI) is conducting an observational study to evaluate and provide standard treatment for individuals with various eye diseases. Participants will undergo a series of eye exams and assessments over a period of up to five years, with visits ranging from one to twelve times per year based on their specific condition. The study aims to collect data and specimens to enhance understanding of eye diseases, their inheritance, and the effectiveness of standard treatments. Additionally, it seeks to establish a resource for future research on ocular conditions.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients with eye diseases.
How similar studies have gone: Other studies focusing on the natural history and treatment of ocular diseases have shown promise, indicating that this approach is supported by previous findings.
Who can join: the full rules
Show full inclusion / exclusion criteria
* INCLUSION CRITERIA: To be eligible, the following inclusion criteria must be met, where applicable. 1. Have a diagnosed, undiagnosed or suspected eye disease. 2. Have the ability to understand and sign an informed consent or have a parent/legal guardian do so if they are minor children or a legally authorized representative (LAR) to provide consent for adults without consent capacity. EXCLUSION CRITERIA: A participant is not eligible if any of the following exclusion criteria are present. 1. Are unwilling to give informed consent or assent when applicable. 2. Are unwilling or unable to be followed as clinically indicated. 3. Have a systemic disease that compromises the ability of NEI clinicians to provide adequate ophthalmologic examination or treatment.
Where it's running
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National Institutes of Health Clinical Center
Bethesda, Maryland, United States Recruiting
Study contacts
- Principal investigator: Awilda V Holland, R.N. — National Eye Institute (NEI)
- Study coordinator: Awilda V Holland, R.N.
- Email: aholland@nei.nih.gov
- Phone: (301) 435-1831
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.