Evaluating adenoma recurrence after specific endoscopic procedures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to compare the recurrence rates of adenomas in non-pedunculated colonic lesions following two different endoscopic mucosal resection techniques: one with margin marking and the other with thermal margin ablation. Patients aged 18 and older, who are scheduled for colonoscopy to evaluate and remove colon polyps of 20 mm or larger, will be included. The study will assess the effectiveness of these techniques in preventing adenoma recurrence, providing valuable insights into optimal treatment approaches.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age 18 years or older
2. Ability to provide informed consent
3. Patient scheduled to undergo colonoscopy for the evaluation and removal of colon polyps
4. Non-pedunculated polyps ≥ 20 mm size

Exclusion Criteria:

1. Pedunculated polyps
2. Inflammatory bowel disease
3. Inability to provide informed consent
4. Lesions \< 20 mm in size (largest dimension)
5. Lesion involves the lips of the ileocecal valve, is located at the appendiceal orifice and/or is fully circumferential.
6. Any standard contraindication, including pregnancy, to anesthesia and/or colonoscopy

Where it's running

• AdventHealth
  Orlando, Florida, United States Recruiting

Study contacts

• Principal investigator: Dennis Yang, MD — AdventHealth
• Study coordinator: Diana Paredes, RN
• Email: Diana.Paredes@adventhealth.com
• Phone: 407-303-5503

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.