Evaluating active schistosomiasis infections in travelers and migrants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical investigation aims to assess the percentage of travelers and migrants diagnosed with chronic schistosomiasis who have active infections at the time of evaluation. The study employs a comprehensive diagnostic approach that includes clinical assessments, laboratory tests, and diagnostic features such as microscopy and PCR. Participants will undergo standardized evaluations, including blood and urine sampling, to determine the presence of active infection. The findings will help improve diagnostic practices for schistosomiasis in affected populations.

Why it matters

Who can join: the full rules

Inclusion criteria

1. diagnosis of chronic schistosomiasis (\>3 months after last potential exposure) according to site-specific diagnostic practice
2. signed informed consent (and assent for minors).

Exclusion criteria

1. age below 5 years;
2. exposure to praziquantel after the last potential exposure to schistosomes
3. acute infection, i.e. likely infection \<3 months before presentation

Where it's running

• Institute of Tropical Medicine (ITM)
  Antwerp, Belgium Recruiting
• IRCCS Policlinico Sant'Orsola
  Bologna, Bo, Italy Recruiting
• IRCCS Sacro Cuore Don Calabria
  Negrar, Vr, Italy Recruiting
• Tropical Medicine Unit of Hospital de Poniente
  Almería, Spain Recruiting
• Vall d'Hebron University Hospital
  Barcelona, Spain Recruiting
• Universitätsklinikum Hamburg-Eppendorf
  Hamburg, Germany Not yet recruiting

Study contacts

• Principal investigator: Federico Giovanni Gobbi — IRCCS Sacro Cuore Don Calabria
• Study coordinator: Elvia Malo
• Email: ricerca.clinica@sacrocuore.it
• Phone: +390456013111

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.