Evaluating ActiGraft for healing abdominal surgical wounds

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of ActiGraft in promoting the healing of abdominal surgical wound dehiscence in women. It involves a prospective, single-arm approach with 20 participants who will receive weekly applications of ActiGraft for up to four weeks or until their wounds heal. The outcomes will be compared to a historic matched-control group of 20 patients to assess the efficacy of the treatment. The study aims to provide insights into the potential benefits of ActiGraft in wound management.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \>18 years
* Women that had a laparotomy no more than 3 weeks before accrual.
* Surgical wound dehiscence that requires a secondary closure.
* Time from wound dehiscence \>24 hours and \<6 days.
* The open wound includes epidermis, dermis and sub cutaneous fat.
* The patient can sign an informed consent form.

Exclusion Criteria:

* Patients with necrotizing fasciitis
* Patients with fascial dehiscence
* Cannot withdraw blood in the required amount (up to 18 mL per week).
* Known coagulation problems, abnormal thrombocytes level or if heparin is given intravenously. Subjects who are taking oral anti-coagulants or anti-agreganrts will not be excluded.
* Pregnancy
* Subject is currently receiving (i.e., within the past 30 days) or scheduled to receive systemic steroids (Prednisone- more than 10mg/d or equivalent).

Where it's running

• Meir Medical Center
  Kfar Saba, Israel Recruiting

Study contacts

• Study coordinator: Sharon Sirota
• Email: sharon@reddress.co.il
• Phone: +972545800765

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Evaluating RD2 Ver.02 for managing anal fistulas

  This study is testing a new treatment called RD2 Ver.02 to see if it can help people with certain types of anal fistulas heal better than a saline solution.

  Recruiting at 9 sites RedDress Ltd. · Los Angeles, California and 9 other locations · NCT05641844

• Evaluating ActiGraft for treating cutaneous wounds

  This study is testing if ActiGraft can help heal different types of wounds, like diabetic foot ulcers and pressure sores, in real-life situations.

  Recruiting RedDress Ltd. · Las Vegas, Nevada · NCT04699305

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.