Evaluating a virtual reality platform for rehabilitation in patients with brain injuries and cerebral palsy

Verify the Performance in Clinical Practice of the Immersive Virtual Reality Platform GRAIL (Gait Real-time Analysis Interactive Lab) in Children and Adolescents Affected by Congenital and Acquired Brain Injury and Determine Any Secondary Effects.

IRCCS Eugenio Medea · NCT06317519

This study tests if a virtual reality program can help people with brain injuries and cerebral palsy improve their walking, balance, and coordination during rehab.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages5 Years to 20 Years
SexAll
SponsorIRCCS Eugenio Medea (other)
Locations1 site (Bosisio Parini, Lecco)
Trial IDNCT06317519 on ClinicalTrials.gov

What this trial studies

This observational study aims to assess the effectiveness of the Gait Real-time Analysis Interactive Lab (GRAIL), an immersive virtual reality platform designed to improve gait, balance, and coordination in patients with acquired brain injuries and cerebral palsy. The GRAIL combines an instrumented treadmill with motion capture technology to create a personalized rehabilitation experience that incorporates principles of motor learning. Participants will engage in high-intensity, repetitive tasks within a virtual environment tailored to their individual needs, potentially enhancing their rehabilitation outcomes.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals with acquired brain injuries or cerebral palsy who can follow verbal instructions and have a Gross Motor Function Classification System score of I to III.

Not a fit: Patients with severe spasticity, cognitive disabilities, or significant auditory or visual impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve the quality of life for patients with neuromotor disorders by enhancing their mobility and independence.

How similar studies have performed: Previous studies utilizing virtual reality in rehabilitation have shown promising results, indicating that this approach is supported by existing evidence.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Capable of following verbal requests
* Gross Motor Function Classification System score I to III

Exclusion Criteria:

* Severe spasticity
* Severe cognitive disability
* Severe auditory or visual disability

Where this trial is running

Bosisio Parini, Lecco

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Acquired Brain Injury, Cerebral Palsy

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.