Evaluating a procedure for treating atrial functional mitral regurgitation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the outcomes of patients with atrial functional mitral regurgitation who have undergone transcatheter edge-to-edge repair in a clinical setting. It is a multicenter, international, retrospective registry that collects data on patient outcomes to assess the effectiveness of this treatment approach. The study aims to provide insights into the routine clinical management of this condition and its implications for patient care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* functional mitral regurgitation
* left ventricular ejection fraction ≥50%

Exclusion Criteria:

* age under 18 years
* known regional wall movement disorders

Where it's running

• Montefiore Medical Center
  The Bronx, New York, United States Recruiting
• St. Michael's Hospital
  Toronto, Canada Recruiting
• Bordeaux University Hospital
  Bordeaux, France Recruiting
• University Hospital Center of Nantes
  Nantes, France Recruiting
• LMU Klinikum
  Munich, Bavaria, Germany Recruiting
• University Hospital Cologne
  Cologne, North Rhine-Westphalia, Germany Recruiting

Study contacts

• Principal investigator: Christos Iliadis, MD — Heart Center, Department III of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Kerpener Straße 62, 50937, Cologne, Germany
• Study coordinator: Philipp von Stein, MD
• Email: philipp.von-stein@uk-koeln.de
• Phone: 646-321-8145

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Valsar­tan for Atrial Functional Mitral Regurgitation (AFMR) — Pilot

  Atrial functional mitral regurgitation is studied to see if valsartan can slow its progression in adults with good heart pump function.

  Recruiting Phase 2/3 Laval University · Québec, Quebec · NCT07539298

• Transcatheter Edge-to-Edge Repair for Atrial Functional Mitral Regurgitation

  This trial tests whether a transcatheter edge-to-edge repair device helps people with atrial functional mitral regurgitation who still have symptoms despite standard therapy.

  Recruiting Beijing Anzhen Hospital · Beijing, Beijing Municipality · NCT07414225

• Transcatheter Mitral and Tricuspid Interventions and Cardiac MRI Registry

  This study will collect imaging and clinical data from adults undergoing transcatheter mitral or tricuspid procedures to see how their heart structure and function change over time using MRI and advanced ultrasound.

  Recruiting Centro Cardiologico Monzino · Milan, Milan · NCT07370467

• Predicting afterload mismatch after transcatheter mitral edge-to-edge repair

  It will test a model to predict which adults having transcatheter mitral valve edge-to-edge repair will develop afterload mismatch after the procedure.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT07019935

• Catheter ablation for people with persistent atrial fibrillation and severe atrial functional mitral regurgitation

  This will test whether adding catheter ablation to usual medicines helps adults with persistent atrial fibrillation and moderate-to-severe or severe atrial functional mitral regurgitation reduce valve leakage and improve symptoms and outcomes.

  Recruiting at 12 sites Beijing Anzhen Hospital · Hefei, Anhui and 16 other locations · NCT06883864

• Assessing risks and outcomes in patients with mitral regurgitation

  This study looks at patients with moderate to severe mitral regurgitation to see what factors might affect their health outcomes and help doctors make better treatment decisions.

  Recruiting Sun Yat-sen University · Guangzhou, Guangdong · NCT06876883

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.