Evaluating a new ultrasound-guided technique for Dupuytren's contracture
Advancing Dupuytren's Contracture Treatment: a Clinical Prospective Study on Ultrasound-Guided Needle Knife Dissection
This study is testing a new ultrasound-guided procedure to see if it can safely improve hand function for people with Dupuytren's contracture while causing fewer problems than traditional surgery.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Mansoura University Hospital Academic / other |
| Locations | 1 site (Al Mansurah, Dakahlia Governorate) |
| Trial ID | NCT06788847 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the safety and effectiveness of an ultrasound-guided needle knife dissection procedure for treating Dupuytren's contracture, a condition that causes hand deformity and dysfunction. The minimally invasive technique is designed to improve hand function while reducing complications associated with traditional surgical methods. Participants will undergo the procedure under ultrasound guidance to ensure precise dissection, with outcomes measured in terms of range of motion and patient satisfaction over a six-month follow-up period.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals diagnosed with Dupuytren's contracture who are willing to undergo the ultrasound-guided needle knife dissection.
Not a fit: Patients who have had previous surgery or needle apponeurotomy on the same hand, or those with active infections or systemic illnesses, may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide patients with a safer and more effective treatment option for Dupuytren's contracture, leading to improved hand function.
How similar studies have performed: While this specific approach is novel, similar minimally invasive techniques have shown promise in treating Dupuytren's contracture in other studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participants diagnosed with Dupuytren's Contracture. * Willing to undergo ultrasound-guided needle knife dissection Exclusion Criteria: * Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand. * Active hand infections, open wounds, or dermatological conditions in the treatment area. * Coagulopathy or use of anticoagulant that cannot be safely paused * Neuromuscular disorders affecting hand function * Pregnancy or breastfeeding * Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease. * Known hypersensitivity to local anesthetics.
Where this trial is running
Al Mansurah, Dakahlia Governorate
- Mansoura University Hospital — Al Mansurah, Dakahlia Governorate, Egypt (Recruiting)
Study contacts
- Study coordinator: Mohamed Maher Elashmawy, MD, PHD.
- Email: mohamedmaherismail@mans.edu.eg
- Phone: +201004303100
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.