Evaluating a new ultrasound-guided technique for Dupuytren's contracture

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the safety and effectiveness of an ultrasound-guided needle knife dissection procedure for treating Dupuytren's contracture, a condition that causes hand deformity and dysfunction. The minimally invasive technique is designed to improve hand function while reducing complications associated with traditional surgical methods. Participants will undergo the procedure under ultrasound guidance to ensure precise dissection, with outcomes measured in terms of range of motion and patient satisfaction over a six-month follow-up period.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Participants diagnosed with Dupuytren's Contracture.
* Willing to undergo ultrasound-guided needle knife dissection

Exclusion Criteria:

* Patients who have undergone previous surgery or needle apponeurotomy for Dupuytren's Contracture on the same hand.
* Active hand infections, open wounds, or dermatological conditions in the treatment area.
* Coagulopathy or use of anticoagulant that cannot be safely paused
* Neuromuscular disorders affecting hand function
* Pregnancy or breastfeeding
* Uncontrolled systemic illnesses, such as poorly managed diabetes or cardiovascular disease.
* Known hypersensitivity to local anesthetics.

Where it's running

• Mansoura University Hospital
  Al Mansurah, Dakahlia Governorate, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed Maher Elashmawy, MD, PHD.
• Email: mohamedmaherismail@mans.edu.eg
• Phone: +201004303100

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• CNT201 collagenase injection for Dupuytren’s: safety and signals of efficacy in adults

  A randomized, placebo-controlled study will test CNT201 injections to see if they are safe and help improve finger contractures in adults with Dupuytren’s disease.

  Recruiting Phase 1/2 Connext · Kippa-Ring, Queensland · NCT07640425

• Using radiation therapy to prevent Dupuytren's contracture recurrence after treatment

  This study is testing if targeted radiation therapy can help prevent Dupuytren's contracture from coming back after treatment in people aged 45 and older.

  Recruiting Dartmouth-Hitchcock Medical Center · Lebanon, New Hampshire · NCT06330545

• Treatment options for Dupuytren's contracture

  This study is testing whether adding a corticosteroid injection to a needle treatment helps people with Dupuytren's contracture move their fingers better.

  Recruiting Phase 4 Regionshospitalet Silkeborg · Silkeborg · NCT05440240

• Evaluating night splinting after needle fasciotomy for Dupuytren's contracture

  This study is testing if wearing a night splint after a needle procedure for Dupuytren's contracture can help prevent the condition from coming back compared to just physical therapy alone.

  Recruiting at 3 sites Uppsala University · Falun, Dalarna County and 2 other locations · NCT05300893

• Evaluating post-surgery radiation treatment for Dupuytren's disease

  This study is testing whether adding radiation treatment after surgery for Dupuytren's disease can help improve hand function and reduce symptoms for patients.

  Recruiting University of Minnesota · Minneapolis, Minnesota · NCT04122313

• Surgical technique to reduce scarring in trigger finger patients with Dupuytren's cord

  This study is testing a new surgical method to help people with trigger finger and Dupuytren's cord heal better with less scarring after surgery.

  Recruiting Mayo Clinic · Rochester, Minnesota · NCT03155854

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.