Evaluating a new tissue glue for catheter insertion sites

Evaluation of a Tissue Glue SecurePortIV on Prevention of Phlebitis and Migration of PICC and Midline Catheters in Adult Patients

NA · University Hospital Ostrava · NCT04900740

This study is testing a new tissue glue to see if it can help prevent problems at the insertion sites of catheters in adults compared to standard care.

Quick facts

PhaseNA
Study typeInterventional
Enrollment250 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity Hospital Ostrava (other)
Locations1 site (Ostrava, Moravian-Silesian Region)
Trial IDNCT04900740 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of a cyanoacrylate tissue glue called Secure PortIV on the insertion sites of peripherally inserted central catheters (PICC) and midline catheters. A total of 250 adult participants will be enrolled, with half receiving the tissue glue and the other half receiving standard care. The study will assess the incidence of mechanical and infective phlebitis, as well as catheter migration, through evaluations conducted on the first and seventh days post-insertion. The goal is to determine if the tissue glue can improve patient outcomes related to catheter use.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who require long-term venous access.

Not a fit: Patients who are pediatric or unable to provide informed consent will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce complications associated with catheter use, improving patient safety and comfort.

How similar studies have performed: While the use of tissue glue in catheter fixation is a novel approach, similar studies have shown promising results in reducing complications.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 18 years of age
* need of long-term venous access
* consent with participation in the study

Exclusion Criteria:

* pediatric population
* not signing the informed consent form

Where this trial is running

Ostrava, Moravian-Silesian Region

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Adult Patients With Mid-term or Long-term Venous Access, peripherally inserted central catheter, midline, cyanoacrylate tissue glue, tissue glue, phlebitis, catheter migration

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.