Evaluating a new scoring system for predicting mortality in cirrhotic patients with gastrointestinal bleeding

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to validate the CAGIB score, a novel prognostic model, for assessing in-hospital mortality in patients with liver cirrhosis experiencing acute gastrointestinal bleeding. The study will compare the performance of the CAGIB score against established scoring systems, such as Child-Pugh and MELD scores, to determine its effectiveness in predicting patient outcomes. Conducted across multiple international centers, the study will involve adult patients presenting with specific symptoms of gastrointestinal bleeding. The goal is to enhance the accuracy of mortality predictions in this high-risk patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with liver cirrhosis;
2. Patients with acute gastrointestinal bleeding presenting with hematemesis, melena, and/or hematochezia;
3. Adults (age≥18 years old).

Exclusion Criteria:

1. Components of Child-Pugh, MELD, and CAGIB scores are not available;
2. In-hospital outcomes are not evaluable.

Where it's running

• São Paulo State University (UNESP), Botucatu Medical School
  São Paulo, São Paulo, Brazil Recruiting
• Beijing Youan Hospital, Capital Medical University
  Beijing, Beijing Municipality, China Recruiting
• First Affiliated Hospital of Fujian Medical University
  Fuzhou, Fujian, China Recruiting
• Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, Hubei, China Recruiting
• First Affiliated Hospital of Nanchang University
  Nanchang, Jiangxi, China Recruiting
• The Six People's Hospital of Dalian
  Dalian, Liaoning, China Recruiting

Study contacts

• Study coordinator: Xingshun Qi, Dr.
• Email: xingshunqi@126.com
• Phone: 18909881019

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.