Evaluating a new PET/CT scan for orbital tumors

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to assess the effectiveness of 18F-AlF-FAPI PET/CT in diagnosing primary and metastatic orbital neoplasms compared to the standard 18F-FDG PET/CT. Participants with suspected or newly diagnosed orbital tumors will undergo both imaging techniques to evaluate their diagnostic accuracy. The study will quantify tumor uptake and record the number of metastatic lesions identified by each method, calculating sensitivity, specificity, and accuracy for comparison.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. patients with suspected or newly diagnosed orbital neoplasms (supporting evidence may include MRI, CT and pathology report);
2. patients who had scheduled both 18F-FDG and 18F-AlF-FAPI PET/CT scans;
3. patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

1. patients with pregnancy;
2. breastfeeding;
3. the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it's running

• Dept. of Nuclear Medicine, Peking University Third Hospital
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Study coordinator: Hui Li
• Email: huilee1990@163.com
• Phone: 86-010-82264935

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.