Evaluating a new mesh for supporting venous grafts in heart surgery
Official title: Multicenter Randomised Prospective Study for External Support Mesh VEST of Venous Coronary Grafts on the Right Territory: Mid-term Clinically Driven Re-rivascularization Events Comparison Between Sites Treated With VEST, Sites Treated With Bare Vein, Sites Treated With Other Conduits and de Novo Lesions on the Native Vessels
Run by Cardiochirurgia E.H. · NCT06877195 · Data updated 2026-11-12
This study is testing a new mesh to see if it can help improve the success of heart surgery by supporting grafts used in bypass procedures for people with heart problems.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 300 (estimated) |
| Sponsor | Cardiochirurgia E.H. Academic / other |
| Locations | 1 site (Roma, Roma) |
| Status | Recruiting |
| Started | March 1, 2025 |
| Main results expected | March 1, 2028 |
| Study ends | May 1, 2028 |
| Registry record updated | March 18, 2025 |
| Trial ID | NCT06877195 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing coronary artery bypass grafting with suitable vein caliber and graft flowmetry.
✕Probably not a fit
Patients who cannot undergo grafting due to inadequate vein caliber or flowmetry will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter randomized prospective study aims to assess the medium-term effectiveness of a new external support mesh, VEST, for venous coronary grafts specifically in the right coronary artery territory. The study will involve clinical and instrumental follow-ups to monitor the patency of these grafts and will compare outcomes between grafts treated with VEST, bare veins, and other conduits. The focus will be on clinically driven re-revascularization events and the emergence of new lesions. This approach seeks to improve the success rates of coronary artery bypass grafting (CABG) procedures.
Why it matters
Potential benefit: If successful, this study could enhance the long-term success of coronary artery bypass grafts, leading to better patient outcomes.
How similar studies have gone: While similar studies have explored graft support techniques, the specific use of the VEST mesh in this context is novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * combined or isolated interventions * adequate vein calibre * adequate graft flowmetry Exclusion Criteria: * inability to implant due to calibre disparity or inadequate flowmetry
Where it's running
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European Hospital
Roma, Roma, Italy Recruiting
Study contacts
- Principal investigator: Luca Paolo Weltert, MD — Unicamillus
- Study coordinator: Luca Paolo Weltert, MD
- Email: lweltert@gmail.com
- Phone: +393478880617
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Temporary heart support with the iVAC 2L device during high-risk coronary procedures
This trial will try the iVAC 2L temporary heart‑support device during high‑risk PCI to help people with severe coronary artery disease stay hemodynamically stable through the procedure.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.