Evaluating a new lung ultrasound technology for shortness of breath

A Validation Study to Evaluate the Performance of Caption Health Lung Guidance and Interpretation

Not applicable Interventional Caption Health, Inc. · NCT05992324

This study is testing a new AI tool to see if it helps non-experts do better lung ultrasound exams for patients who have shortness of breath.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment220 (estimated)
Ages18 Years and up
SexAll
SponsorCaption Health, Inc. Industry-sponsored
Locations4 sites (New Haven, Connecticut and 3 other locations)
Trial IDNCT05992324 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness of Caption LungAI in performing lung ultrasound exams. Participants will undergo two separate lung ultrasound exams: one conducted by an expert without the aid of Caption LungAI and another by a trained non-expert using the technology. The goal is to determine how well the non-expert can capture and interpret lung images with the assistance of this AI tool. The study focuses on patients presenting with shortness of breath and suspected B-lines.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old experiencing shortness of breath and suspected to have B-lines.

Not a fit: Patients in critical condition where a lung ultrasound would not typically be performed will not benefit from this study.

Why it matters

Potential benefit: If successful, this technology could enable non-expert healthcare providers to accurately assess lung conditions, improving patient care and outcomes.

How similar studies have performed: Other studies have shown promise in using AI-assisted imaging technologies, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients over the age of 18
* Patients presenting to the hospital or outpatient setting with shortness of breath and suspected B-lines.

Exclusion Criteria:

* Patients in extremis/in whom a research lung ultrasound would not normally be performed due to other priorities

Where this trial is running

New Haven, Connecticut and 3 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Shortness of BreathLung UltrasoundB-LinesPOCUS by non-expert user
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.