Evaluating a new dosing schedule of olanzapine for schizophrenia treatment

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to assess the safety and efficacy of a titration schedule for olanzapine in patients diagnosed with schizophrenia. Participants will receive a low dose of olanzapine, which is deemed more appropriate than the standard initial dosing, based on their medical conditions. The study will focus on patients who have had schizophrenia for over a year and will exclude those with other psychotic disorders or recent hospitalizations due to worsening symptoms.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Of patients with schizophrenia in accordance with DSM(Diagnostic and Statistical Manual of Mental Disorders)-5 diagnostic criteria, who are judged that administration of low dose is more appropriate than initial recommended dose or standard titration dose of olanzapine to consider medical conditions by investigator
* Patients with the duration of schizophrenia for more than 1 year at screening visit(Visit 1)

Exclusion Criteria:

* Patients diagnosed schizophrenia spectrum and other psychotic disorder(e.g. schizoaffective disorder, etc.), bipolar disorder, depressive disorder, etc., in accordance with DSM(Diagnostic and Statistical Manual of Mental Disorders)-5 diagnostic criteria at screening visit(Visit 1)
* Patients with a history of hospitalization for worsening schizophrenia within 12 weeks at screening visit(Visit 1)

Where it's running

• Kyungbook National university hospital
  Daegu, South Korea Recruiting
• Hanyang University Guri Hospital
  Guri-si, South Korea Not yet recruiting

Study contacts

• Study coordinator: Shin-young Oh
• Email: syoh@boryung.co.kr
• Phone: +82+2-708-8000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.