Evaluating a music therapy tool for measuring awareness in children with disorders of consciousness

Evaluating the Validity, Reliability, and Clinical Utility of the Music Therapy Sensory Instrument for Cognition, Consciousness and Awareness (MuSICCA) in Children and Youth With Prolonged Disorders of Consciousness

Observational The Children's Trust, United Kingdom · NCT04050995

This study is testing a new music therapy tool to see if it can help understand awareness in children with severe disorders of consciousness.

Quick facts

Study typeObservational
Enrollment80 (estimated)
Ages2 Years to 18 Years
SexAll
SponsorThe Children's Trust, United Kingdom Academic / other
Locations3 sites (Atlanta, Georgia and 2 other locations)
Trial IDNCT04050995 on ClinicalTrials.gov

What this trial studies

This research evaluates the MuSICCA, a music therapy assessment tool designed for children with prolonged disorders of consciousness, such as the vegetative state and minimally conscious state. The study aims to assess the validity, reliability, and clinical utility of the MuSICCA by comparing its results to established measures like the Coma Recovery Scale-Revised. It will involve 80 participants aged 2-18 who have been assessed as having a disorder of consciousness. The study is observational and does not involve a control group, ensuring all participants receive the assessment measures.

Who should consider this trial

Good fit: Ideal candidates for this study are children aged 2-18 who have been assessed as having a disorder of consciousness.

Not a fit: Patients with known hearing impairments, profound visual impairments, or seizure disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a reliable tool for accurately diagnosing and assessing awareness in children with disorders of consciousness, leading to better care and treatment.

How similar studies have performed: Previous studies have successfully validated similar assessment tools for adults, but this approach for children is novel and untested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Between 2-18 years of age
* Assessed by the interdisciplinary team as having a disorder of consciousness
* Be under active investigation for diagnosis of DOC

Exclusion Criteria:

* Known hearing impairments
* Known profound visual impairments
* Known musicogenic epilepsy
* Seizure disorders that cause frequent and/or prolonged seizures
* English not first language

Where this trial is running

Atlanta, Georgia and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Disorder of Consciousness
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.