Evaluating a model to predict acute kidney injury in critically ill patients
Evaluation of U-AKIpredTM for Predicting AKI in Critically Ill Patients Within 12 Hours: a Multicenter Prospective Cohort Study
This study is testing a new tool to see if it can help doctors predict kidney problems in critically ill patients within the first 12 hours of their ICU stay.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Second Affiliated Hospital, School of Medicine, Zhejiang University Academic / other |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06496555 on ClinicalTrials.gov |
What this trial studies
This study aims to assess the effectiveness of U-AKIpredTM in predicting acute kidney injury (AKI) in critically ill patients within 12 hours of ICU admission. It involves a multicenter prospective cohort design where AKI is diagnosed based on the Kidney Disease Improving Global Outcomes (KDIGO) criteria. The evaluation will focus on various aspects including overall fitting efficiency, calibration performance, discrimination performance, and clinical utility of the prediction model.
Who should consider this trial
Good fit: Ideal candidates include critically ill patients over 18 years old who have been in the ICU for more than 24 hours.
Not a fit: Patients who have pre-existing kidney conditions or have undergone kidney dialysis or transplantation will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved early detection and management of acute kidney injury in critically ill patients.
How similar studies have performed: Other studies have shown promise in using predictive models for AKI, but the specific approach of U-AKIpredTM is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * critically ill patients who stayed in ICU for over 24 h; * patients older than 18 years of age. Exclusion Criteria: * patients who admitted in ICU had been diagnosed acute kidney injury; * patients who admitted in ICU had been diagnosed acute kidney disease; * patients who admitted in ICU had been diagnosed chronic kidney disease; * patients who admitted in ICU had performed kidney dialysis; * patients who admitted in ICU had performed kidney transplantation; * Pregnant women.
Where this trial is running
Hangzhou, Zhejiang
- 2nd Affiliated Hospital, School of Medicine, Zhejiang University — Hangzhou, Zhejiang, China (Recruiting)
Study contacts
- Study coordinator: Tao Sun, Doctor
- Email: stzr@zju.edu.cn
- Phone: 0571-87783752
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.