Evaluating a guide for monitoring child development in rural India and Guatemala

An Individualized Approach to Promote Nurturing Care in Low and Middle Income Countries: a Hybrid Effectiveness/Implementation Trial of the International Guide for Monitoring Child Development

Not applicable Interventional Brigham and Women's Hospital · NCT04665297

This study is testing a new guide to help monitor child development in rural areas of India and Guatemala to see if it can improve outcomes for children under 2 years old.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment624 (estimated)
Ages0 Months to 24 Months
SexAll
SponsorBrigham and Women's Hospital Academic / other
Locations2 sites (Tecpán Guatemala and 1 other locations)
Trial IDNCT04665297 on ClinicalTrials.gov

What this trial studies

This study aims to assess the effectiveness and implementation of the International Guide for Monitoring Child Development (GMCD) in rural settings of India and Guatemala. It involves a parallel-arm cluster randomized trial where children under 2 years old will receive either the GMCD intervention or a control for 12 months, followed by a crossover for control clusters. The study will evaluate developmental outcomes using the Bayley Scales of Infant Development and nurturing care through the Home Observation for Measurement of the Environment. Additionally, it will explore barriers and facilitators to implementation using the RE-AIM framework.

Who should consider this trial

Good fit: Ideal candidates are children aged 0-24 months receiving health services from designated frontline health workers in Guatemala or India.

Not a fit: Children who are critically ill or whose caregivers do not provide informed consent may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could significantly improve early child development outcomes in low- and middle-income countries.

How similar studies have performed: Previous studies have shown promise in similar approaches to improving child development outcomes, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* age 0-24 months at the time of enrollment visit
* receiving health services from frontline health workers of Maya Health Alliance (Guatemala), Mahatma Gandhi Institute (India) or their local partners

Exclusion Criteria:

* children who are critically ill and are judged by the frontline health worker to require hospitalization or center-based care
* children whose caregivers do not provide informed consent for the study

Where this trial is running

Tecpán Guatemala and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Child DevelopmentGuatemalaIndiaEarly Child Development
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.