Evaluating a glass hybrid material for treating class III dental caries

Clinical Performance of Glass Hybrid Restorations in the Treatment of Class III Lesions: A Randomized Clinical Trial

Not applicable Interventional Hacettepe University · NCT05843734

This study is testing a new glass hybrid material for filling cavities in teeth to see if it works better than a standard composite resin for adults with similar dental issues.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years to 50 Years
SexAll
SponsorHacettepe University Academic / other
Locations2 sites (Ankara and 1 other locations)
Trial IDNCT05843734 on ClinicalTrials.gov

What this trial studies

This clinical trial is a double-blinded, split-mouth, randomized study that compares the performance of a glass hybrid restorative material (Equia Forte) against an anterior composite resin (G-aenial Anterior) in treating class III dental caries. Participants aged 18 and older with at least two symmetrical class III lesions will have their teeth restored using both materials, with evaluations conducted after 24 months based on FDI criteria. The study aims to provide insights into the effectiveness and longevity of the glass hybrid material in dental restorations.

Who should consider this trial

Good fit: Ideal candidates are healthy adults aged 18 and older with at least two class III lesions on symmetrical teeth in the right and left arches.

Not a fit: Patients with systemic disorders, severe periodontal issues, or those who cannot attend follow-up appointments may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment options for patients with class III dental caries, potentially enhancing restoration longevity and patient satisfaction.

How similar studies have performed: While this approach is not widely tested, similar studies evaluating restorative materials have shown promising results in dental restoration effectiveness.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The participant must be at least 18 years of age or older
* The participant has at least two class III lesions and the lesions are in symmetrical teeth located in the right and left arch
* The lesion covers at most 2/3 and at least 1/3 of the dentin
* Participant voluntarily signing the informed consent form
* The participant does not have a physical disability that may prevent them from coming to the control.
* Absence of a periapical pathology in the involved tooth

Exclusion Criteria:

* Having systemic disorders that may prevent the participant from regularly attending treatment and control appointments.
* Having severe periodontal problems in the tooth planned to be treated
* Absence of the opposite of the tooth and not participating in chewing
* Lesions which is limited with the enamel tissue
* Teeth with lesions that are too large to be restored
* Patients with anterior malocclusion
* Patients with parafunctional habits.
* Mentally disabled patients.

Where this trial is running

Ankara and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Class III Dental CariesGlass hybrid restorativeClass IIIAnterior restorationFDI criteria
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.