Evaluating a diagnostic algorithm for sarcopenic obesity

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This research project investigates sarcopenic obesity, a condition marked by high body fat and low muscle mass, focusing on muscle function. It aims to validate the ESPEN-EASO algorithm for diagnosing this condition by enrolling 75 subjects with sarcopenic obesity and a control group of 75 with non-sarcopenic obesity. The study will examine the consistency of diagnostic criteria in relation to biomarkers and functional outcomes, while also assessing additional variables through questionnaires and tests. Ethical standards will be upheld through informed consent and privacy protection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* BMI equal more than 30
* Caucasians

Exclusion Criteria:

* any disease or medication that can significantly affect body composition (eg.malignant diseases in the last 5 years, autoimmune diseases, neurological diseases, syndromic obesity),
* level of physical activity more than 3 METS
* alcohol intake more than 140g/wk for M and 70g/wk for F
* participation in a weight-reducing program (last 3 months),
* impossibility to perform DXA exam
* pregnancy and breast-feeding.

Where it's running

• Azienda Policlinico Umberto I
  Rome, Rm, Italy Recruiting

Study contacts

• Study coordinator: Elisa Giannetta
• Email: elisa.giannetta@uniroma1.it
• Phone: 0039-0649970711

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Myokines in metabolic and endocrine diseases linked to sarcopenia

  This study tests whether myokines can serve as biomarkers or drivers of sarcopenia and sarcopenic obesity in people with metabolic or endocrine diseases.

  Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Woluwe-Saint-Pierre - Sint-Pieters-Woluwe · NCT07703683

• Combined resistance training and high-protein diet to help frailty in sarcopenic obesity women

  This trial tests whether adding supervised resistance exercise to a high-protein diet helps frailty in obese, sarcopenic women.

  Recruiting Cairo University · El-Sheikh Zayed City · NCT07627919

• How obesity affects daily activities and physical abilities in older adults

  This study tests how excess weight in people over 65 impacts daily tasks and physical performance, comparing obese seniors to normal-weight peers.

  Recruiting Istituto Auxologico Italiano · Oggebbio · NCT07614464

• GLP-1 drug effects on muscle and bone during weight loss

  It tests whether GLP-1–based weight-loss medication (tirzepatide) plus a lifestyle program changes muscle and bone in adults 18–50 with obesity (BMI 30–40).

  Recruiting Phase 4 Pennington Biomedical Research Center · Baton Rouge, Louisiana and 1 other locations · NCT07154719

• Eccentric exercise program for older adults with heart failure and muscle loss

  This study is testing a 12-week exercise program for older adults with heart failure and muscle loss to see if it can help them get stronger and feel better.

  Recruiting at 2 sites Universita di Verona · Verona, Verona and 1 other locations · NCT06826963

• Understanding Sarcopenic Obesity in COPD Patients

  This study is trying to see how common sarcopenic obesity is in people with COPD and how it affects their breathing, disease severity, and quality of life.

  Recruiting IRCCS San Raffaele Roma · Roma, Roma · NCT06822504

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.