Evaluating a desensitizer for tooth sensitivity after bleaching
Assessment of the Effects of Bio-active Desensitizing Materials on the Bleaching Efficacy and Reduction of Tooth Sensitivity Caused by Vital In-office Bleaching: A Randomized Controlled Clinical Trial
This study is testing if a special gel can help reduce tooth sensitivity after professional teeth whitening compared to a fluoride gel and a placebo.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 51 (estimated) |
| Ages | 18 Years to 35 Years |
| Sex | All |
| Sponsor | King Abdullah University Hospital Academic / other |
| Locations | 1 site (Irbid) |
| Trial ID | NCT06532526 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to assess the effectiveness of a bioactive glass desensitizer in reducing tooth sensitivity that occurs after in-office vital tooth bleaching. Participants will be randomly assigned to receive either the bioactive desensitizer, a fluoride gel, or a placebo gel without desensitizing agents. The study will measure the incidence, intensity, and duration of tooth sensitivity, as well as the impact on tooth shade following the bleaching process. The trial will be double-blinded to ensure unbiased results.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 18 to 30 with at least eight maxillary anterior teeth that are C2 shade or darker and no history of tooth sensitivity.
Not a fit: Patients with active caries, periodontal diseases, or those who have previously undergone tooth bleaching may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a more effective way to manage tooth sensitivity for patients undergoing in-office bleaching procedures.
How similar studies have performed: Other studies have shown varying degrees of success with desensitizing agents in dental procedures, but this specific approach using a bioactive glass desensitizer is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least eight maxillary anterior teeth present. * Age between 18 and 30 years Smokers * The selected teeth has a mean shade of C2 or darker (Vitapan Classical, Vita-Zahnfabrik, Sa¨ckingen, Germany) * Good general and oral health (no visible plaque or gingivitis) * No restorations or carious lesions on the buccal surfaces of the anterior teeth to be whitened * No history of tooth sensitivity * No use of a desensitizing agent or desensitizing toothpaste in the past six months Exclusion Criteria: * Active caries and/or periodontal diseases (gingivitis and recession) or wasting diseases * Smokers * Pregnant/lactating women * Patients who have bleached their teeth previously * No schedule availability
Where this trial is running
Irbid
- Jordan University of Science and Technology — Irbid, Jordan (Recruiting)
Study contacts
- Principal investigator: Ghada A Maghaireh — Jordan University of Science and Technology
- Study coordinator: Ghada A Maghaireh
- Email: gmaghair@just.edu.jo
- Phone: 0798809296
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.