Evaluating a cough-based algorithm for diagnosing COPD

A Clinical Validation Study to Evaluate the Diagnostic Accuracy of a Cough-based Auxiliary Diagnosis Algorithm for Chronic Obstructive Pulmonary Disease (COPD)

Observational Ruijin Hospital · NCT06082791

This study is testing a new tool that uses cough sounds to help diagnose COPD in patients so they can check their lung health at home.

Quick facts

Study typeObservational
Enrollment500 (estimated)
Ages40 Years and up
SexAll
SponsorRuijin Hospital Academic / other
Locations1 site (Shanghai, Shanghai)
Trial IDNCT06082791 on ClinicalTrials.gov

What this trial studies

This study aims to validate a cough-based diagnostic algorithm designed to assist in the diagnosis of Chronic Obstructive Pulmonary Disease (COPD). By analyzing cough characteristics such as amplitude, frequency, and waveform, the algorithm seeks to provide an auxiliary diagnosis and predict lung function. The ultimate goal is to develop a portable tool that patients can use at home for rapid assessment of their condition. The study will involve patients with stable COPD to ensure accurate evaluation of the algorithm's performance.

Who should consider this trial

Good fit: Ideal candidates for this study are patients aged 40 and older with a stable diagnosis of COPD.

Not a fit: Patients experiencing acute exacerbations of respiratory symptoms or those with significant comorbid conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to a convenient and effective home-based tool for diagnosing and monitoring COPD.

How similar studies have performed: While the approach of using cough characteristics for diagnosis is innovative, similar studies have shown promise in utilizing algorithms for respiratory conditions, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* patients with stable COPD were recruited for this study. Inclusion criteria were age ≥40 years and a diagnosis of COPD

Exclusion Criteria:

* Exclusion criteria were acute exacerbations of respiratory symptoms within the past 2 weeks or significant comorbid cardiovascular, neurological, musculoskeletal, immunological, or infectious diseases.

Where this trial is running

Shanghai, Shanghai

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions COPDCoughAlgorithm
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.