Evaluating 7 Tesla MRI for foot and ankle conditions
High-Resolution MRI (7 Tesla) Findings of the Plantar Plate Compared with Current Clinical Standard Sequences (1.5 or 3 Tesla) and Surgical Reference Standard
This study is testing whether a powerful 7 Tesla MRI can give clearer pictures of foot and ankle problems, like tears and neuromas, to help doctors diagnose these issues better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 80 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Balgrist University Hospital Academic / other |
| Locations | 1 site (Zurich, Canton of Zurich) |
| Trial ID | NCT04441983 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the effectiveness of 7 Tesla MRI in providing detailed images of the foot and ankle anatomy, particularly focusing on conditions such as plantar plate tears, Morton neuroma, and tendon and ligament tears. Participants will include patients with specific pathologies confirmed by lower strength MRI scans, as well as asymptomatic individuals to study normal microanatomy. The study will compare findings from 7 Tesla MRI with standard clinical sequences to enhance diagnostic accuracy.
Who should consider this trial
Good fit: Ideal candidates include adults aged 18 and older with specific foot and ankle pathologies confirmed by prior MRI scans.
Not a fit: Patients with previous foot surgeries involving metal implants or those with MRI contraindications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnostic capabilities for foot and ankle conditions, allowing for better treatment planning.
How similar studies have performed: While the use of 7 Tesla MRI is relatively novel, similar studies have shown promise in enhancing imaging quality for various anatomical regions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Informed consent as documented by signature (Appendix Informed Consent Form) * at least 18 years old * Study group: Patients with specific pathologies (i.e. Morton neuroma, tendon tears, plantar plate tears) as proven by 1,5 or 3T MRI or asymptomatic subjects (to look at the normal microanatomy of different structures, mainly the plantar plate) * Control group: No evidence of the respective pathology. Exclusion Criteria: * previous foot surgery with metal in vivo * pregnancy or breast feeding * any MRI contra-indications
Where this trial is running
Zurich, Canton of Zurich
- Balgrist University Hospital — Zurich, Canton of Zurich, Switzerland (Recruiting)
Study contacts
- Principal investigator: Reto Sutter, MD — Balgrist University Hospital
- Study coordinator: Christoph Germann, MD
- Email: christoph.germann@balgrist.ch
- Phone: +41443863322
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.