Evaluating 100 Hz Tetanic Stimulation for Diagnosing Neuromuscular Block

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to assess the feasibility of using 100 Hz tetanic stimulation with an electromyography device to exclude postoperative residual neuromuscular block in patients. It involves monitoring electric responses from the musculus digiti minimi after supramaximal stimulation of the ulnar nerve. Patients are categorized based on their baseline electroneurographic findings, and the study investigates the development of fatigue during tetanic stimulation in both normal and abnormal ENG groups. The study seeks to establish a 'safety margin' for neuromuscular junction monitoring that is not typically provided by standard methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA 1-3;
* BMI 18.5-25 (normal body weight);
* patient is in supine position with one arm accessible.

Exclusion Criteria:

* diseases with impaired neuromuscular function (myopathies, severe liver and kidney failure);
* drugs affecting neuromuscular function (magnesium, aminoglycosides);
* pregnancy (pregnancy tests are carried out in women of childbearing age to rule out pregnancy);
* breast-feeding;
* acute surgery

Where it's running

• University of Debrecen Medical Center, Department of Anesthesiology and Intensive Care
  Debrecen, Hungary Recruiting
• Department of Anesthesiology and Intensive Care, University of Debrecen
  Debrecen, Hajdú-Bihar, Hungary Not yet recruiting

Study contacts

• Study coordinator: Adrienn Pongrácz, MD PhD
• Email: pongadri@gmail.com
• Phone: +36302390132

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.