European venous disease registry for lower limbs
European Venous Registry
This project collects health and treatment information over ten years to see which treatments and outcomes occur in adults with new imaging-confirmed deep venous disease of the lower limbs, including the iliac, common femoral veins, or the inferior vena cava.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | IRCCS San Raffaele Academic / other |
| Locations | 10 sites (Marseille, France and 9 other locations) |
| Trial ID | NCT06906250 on ClinicalTrials.gov |
What this trial studies
The European Venous Registry is an international observational registry enrolling adults with a new imaging-confirmed diagnosis of acute or chronic deep venous disease affecting the iliac and/or common femoral veins or the inferior vena cava. Participating centers record diagnostic imaging, treatments (including interventions), follow-up outcomes, and patient-reported measures over a ten-year period. No experimental treatments are assigned by the registry; data are collected from routine clinical care. The goal is to compile long-term outcome data to inform clinical decision-making and guideline development.
Who should consider this trial
Good fit: Adults (18+) with a new imaging-confirmed diagnosis of acute or chronic lower limb deep venous disease involving the iliac and/or common femoral veins, with or without extension to the inferior vena cava, who can give consent.
Not a fit: People under 18, those unable to consent, and patients with isolated upper limb DVT, isolated deep vein thrombosis below the common femoral vein, isolated superficial venous disease, central venous thrombosis, or isolated varicose veins are not included and therefore would not benefit from enrollment.
Why it matters
Potential benefit: If successful, the registry could help doctors choose better treatments and improve outcomes for people with deep venous disease of the legs.
How similar studies have performed: Previous regional and national venous registries have successfully contributed outcome data and informed practice, so this approach builds on established observational methods rather than being entirely novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with an imaging-confirmed new diagnosis of acute or chronic lower limb deep venous disease involving the iliac and/or common femoral veins, with or without extension to the inferior vena cava, or patients with an imaging-confirmed new diagnosis involving the IVC only. * Consent to enter registry. Exclusion Criteria: * Unable to consent to enter into registry. * Isolated upper limb DVT. * Central venous thrombosis (e.g. superior vena cava obstruction). * Isolated deep vein thrombosis below the common femoral vein. * Isolated superficial venous thrombosis. * Isolated superficial venous thrombophlebitis. * Isolated varicose veins. * Aged \<18 years.
Where this trial is running
Marseille, France and 9 other locations
- Department of Vascular Surgery — Marseille, France, France (Recruiting)
- European Venous Center — Aachen, Germany, Germany (Recruiting)
- Clinic of Vascular and Endovascular Surgery at Athens Medical Group — Athens, Greece, Greece (Recruiting)
- Interventional Radiology, Galway University Hospitals — Galway, Ireland, Ireland (Recruiting)
- IRCCS San Raffaele Hospital — Milan, Italy, Italy (Recruiting)
- Department of Vascular and Endovascular Surgery, Erasmus Medical Centre — Rotterdam, Netherlands, Netherlands (Recruiting)
- Vascular and Endovascular Department, Viamed Hospitals — Madrid, Spain, Spain (Recruiting)
- Department of Cardiovascular Surgery, Acibadem University School of Medicine, — Istanbul, Turkey, Turkey (Türkiye) (Recruiting)
- North Bristol NHS Trust — Bristol, United Kingdom, United Kingdom (Recruiting)
- St Thomas' Hospital — London, United Kingdom, United Kingdom (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.