Establishing a national cohort for juvenile recurrent respiratory papillomatosis in France

Juvenile Recurrent Respiratory Papillomatosis: Establishment of a French National Cohort (PRR : National Cohort " REPA ")

Observational Imagine Institute · NCT06000527

This study aims to gather information about juvenile recurrent respiratory papillomatosis in children in France to understand the disease better and improve treatment options.

Quick facts

Study typeObservational
Enrollment200 (estimated)
SexAll
SponsorImagine Institute Academic / other
Locations1 site (Paris)
Trial IDNCT06000527 on ClinicalTrials.gov

What this trial studies

This observational study aims to establish the epidemiology of juvenile recurrent respiratory papillomatosis (RRP), the most common benign laryngeal tumor in children, in France. It will collect data from reference centers to better understand the disease's epidemiology, risk factors, genetic susceptibility, and clinical manifestations. The study will also evaluate the efficacy of existing therapies and preventive measures to create standardized treatment guidelines. By gathering this data, the study seeks to fill the gap in the current lack of epidemiological information on RRP in France.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with juvenile recurrent respiratory papillomatosis who are under 18 years of age.

Not a fit: Patients who object to the collection of their personal data will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved understanding and management of juvenile recurrent respiratory papillomatosis, ultimately enhancing patient care.

How similar studies have performed: While this study is focused on establishing a national cohort, similar studies in other countries have successfully gathered epidemiological data on RRP, indicating potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with juvenile PRR (disease onset before age 18)
* Followed in the :

  * The MALO CRMR
  * One of the MALO network's CCMRs
  * One of the main correspondent centers

Exclusion Criteria:

* Patients objecting to the collection of their personal data
* Parents of minor patients objecting to the collection of their child's personal data

Where this trial is running

Paris

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Juvenile Recurrent Respiratory Papillomatosis
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.