Establishing a breast tumor tissue repository from core biopsies
Core Biopsies of Breast Tumor Tissue Repository
This study is creating a collection of breast tumor samples from patients with newly diagnosed breast cancer to help researchers learn more about the disease and improve treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 400 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Southern California Academic / other |
| Locations | 1 site (Los Angeles, California) |
| Trial ID | NCT02250352 on ClinicalTrials.gov |
What this trial studies
This observational study aims to create a repository of breast tumor tissue collected from core biopsies at the University of Southern California's Norris Comprehensive Cancer Center. The study will gather baseline and follow-up samples from patients with newly diagnosed breast cancer, allowing researchers to analyze tumor biology, proteins, and genes. The collected data will also include demographic and clinical information to support future research on breast cancer treatment and outcomes. The repository will facilitate the distribution of de-identified samples for various breast cancer-related studies.
Who should consider this trial
Good fit: Ideal candidates include patients with newly diagnosed breast cancer who are undergoing core needle biopsies.
Not a fit: Patients with bleeding disorders or those on anticoagulant or antiplatelet medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding of breast cancer biology and the development of better therapies and diagnostic tests.
How similar studies have performed: Other studies have successfully established tissue repositories for cancer research, indicating a promising approach for advancing breast cancer understanding.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Known or suspected breast cancer * Known or suspected metastatic solid tumor that originated in the breast per the patient's medical history Exclusion Criteria: * Inability to sign informed consent * Known bleeding disorder * Use of anticoagulant medications (heparin, warfarin, etc.) within one week prior to biopsy * Use of antiplatelet medications (aspirin, clopidogrel, etc.) within one week prior to biopsy
Where this trial is running
Los Angeles, California
- USC Norris Comprehensive Cancer Center — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Evanthia Roussos-Torres, M.D. — University of Southern California
- Study coordinator: Zeno Ashai
- Email: zeno.ashai@med.usc.edu
- Phone: 323-865-0463
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.