Clinical trial Recruiting at 1 site Interventional Ages 18 to 75

Erector spinae plane block versus interlaminar epidural steroid injection for lumbar disc herniation pain

Official title: Comparison of the Effectiveness of Lumbar Erector Spinae Plane Block and Lumbar Interlaminar Epidural Steroid Injection in Patients With Lumbar Disc Herniation.

Run by Diskapi Teaching and Research Hospital · NCT07184554 · Data updated 2026-11-12

This study will test whether ultrasound-guided erector spinae plane blocks or fluoroscopy-guided interlaminar epidural steroid injections give better short-term pain and function relief for adults with L4-5 or L5-S1 lumbar disc herniation who haven't improved with conservative care.

Quick facts

Study typeInterventional
Ages18 Years to 75 Years
SexAll
Enrollment80 (estimated)
SponsorDiskapi Teaching and Research Hospital
Academic / other
Locations1 site (Ankara)
StatusRecruiting
StartedSeptember 20, 2025
Main results expectedDecember 30, 2025
Study endsDecember 30, 2025
Registry record updatedSeptember 25, 2025
Trial IDNCT07184554 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with MRI-confirmed L4-L5 or L5-S1 lumbar disc herniation causing radicular pain, with VAS >5 for at least six weeks and inadequate response to conservative treatments, who have not had prior lumbar surgery.

Probably not a fit

Patients with prior lumbar surgery, spinal deformity or stenosis, uncontrolled diabetes, active infection, coagulopathy, rheumatologic disease, psychiatric comorbidity, or drug allergies are not expected to benefit and are excluded.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational follow-up of patients treated routinely at a single clinic with either ultrasound-guided lumbar erector spinae plane (LESP) block or fluoroscopy-guided lumbar interlaminar epidural steroid injection (LESI) for radicular pain from L4-5 or L5-S1 disc herniation. Baseline pain and function are recorded from patient files, and outcomes are measured using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) at 2, 6, and 12 weeks after the procedure. Patients are not randomized or assigned to groups for the purposes of the study and receive the usual clinical care determined by their treating team. The study compares real-world effectiveness of the two commonly used interventional options in patients who failed conservative therapy.

Why it matters

Potential benefit: If successful, results could help clinicians choose the injection technique that provides faster or more durable pain relief and functional improvement, potentially reducing the need for surgery.

How similar studies have gone: Fluoroscopy-guided epidural steroid injections have an established but mixed short-term evidence base for radicular pain, while ultrasound-guided erector spinae plane blocks are a newer approach with limited comparative data.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with chronic low back pain caused by L4-L5 and L5-S1 lumbar disc herniation accompanied by radicular pain, including those diagnosed by MRI, will be included.
* Patients with low back pain above VAS 5 for more than 6 weeks will be included.
* Failure of pain treatment with conservative methods such as analgesics and physical therapy

Exclusion Criteria:

* Patients who have previously undergone lumbar surgery,
* Patients with spinal deformity and stenosis,
* Patients with uncontrolled diabetes
* Patients allergic to the drugs to be used will not be included in the study.
* Presence of psychiatric comorbidity
* Local or systemic infection
* Coagulopathy
* Presence of rheumatological disease

Where it's running

  • Etlik City Hospital
    Ankara, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.