Epidemiology and clinical features of human anaplasmosis in Alsace
Epidemiological, Clinical and Biological Characteristics of Human Anaplasmosis Cases in Alsace: a Retrospective and Multicenter Study
This project will see how Anaplasma phagocytophilum infections present and progress in adults in Alsace using PCR-confirmed cases.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Trial ID | NCT07312474 on ClinicalTrials.gov |
What this trial studies
This is an observational project enrolling adults (≥18) with PCR-confirmed Anaplasma infection seen at the Infectious Diseases department of CHU de Strasbourg. Investigators will collect epidemiological data, clinical signs and symptoms, laboratory and biological findings, treatment given, and clinical outcomes. The goal is to characterize typical presentations, frequency of severe complications (for example cytopenias, respiratory distress, macrophage activation), and outcomes in the local Alsace population. Results will be compared with published series from other countries to refine regional recognition and management.
Who should consider this trial
Good fit: Adults aged 18 or older with a PCR-confirmed Anaplasma phagocytophilum infection who agree to participate are ideal candidates.
Not a fit: People without PCR confirmation, children under 18, or anyone who refuses consent are not eligible and will not benefit from this project.
Why it matters
Potential benefit: If successful, the project could help clinicians recognize anaplasmosis earlier in this region, leading to faster treatment and fewer severe complications.
How similar studies have performed: Similar observational case series from the U.S. and several European countries have described clinical patterns and supported doxycycline treatment, so the approach is well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult subjct (≥18 years) * Presenting with a PCR-confirmed infection of Anaplasma Exclusion Criteria: \- Refusal to participate in the study
Where this trial is running
Strasbourg
- Service des Maladies Infectieuses et Tropicales - CHU de Strasbourg - France — Strasbourg, France (Recruiting)
Study contacts
- Study coordinator: Victor GERBER, MD
- Email: victor.gerber@chru-strasbourg.fr
- Phone: 33 3.88.11.67.68
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.