Enhancing cognitive abilities using personalized brain stimulation
Cognitive Enhancement Through Model-based and Individualized Neurostimulation
This study is testing if personalized brain stimulation can improve attention and brain function in healthy adults.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Washington University School of Medicine Academic / other |
| Locations | 1 site (Saint Louis, Missouri) |
| Trial ID | NCT06235970 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effects of transcranial electrical stimulation (tES) on attentional control and brain dynamics in healthy adults. Participants will undergo various stimulation protocols, including conventional methods and individualized approaches based on a neural model, while their brain activity is monitored using electroencephalography (EEG). The study aims to determine how these stimulation methods influence cognitive performance and whether mathematical models can predict changes in brain activity. By comparing active stimulation with sham stimulation, the researchers hope to gain insights into the effectiveness of personalized tES protocols.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 to 45 who are not taking medications that affect cognitive function.
Not a fit: Patients with medical disorders affecting cognitive or motor function, or those with a history of seizures, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved cognitive enhancement techniques for healthy individuals.
How similar studies have performed: Previous studies have shown promise in using tES for cognitive enhancement, but this approach of personalized stimulation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy younger adults (ages 18 to 45). Community-living men, women or non-binary, aged 18-45 Exclusion criteria: * Taking psychotropic medication or medication with cognitive side effects * Medical disorder that affects cognitive or motor function * Past/present head injury associated with loss of consciousness or neurological sequelae * Prior occurrence of seizure of any origin * Skin conditions affecting the scalp * Scalp tattoos * Rashes, sores or open wounds on scalp or face
Where this trial is running
Saint Louis, Missouri
- Washington University — Saint Louis, Missouri, United States (Recruiting)
Study contacts
- Study coordinator: Todd Braver, PhD
- Email: tbraver@wustl.edu
- Phone: 3149354153
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.